Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313205224> ?p ?o ?g. }
- W4313205224 endingPage "370" @default.
- W4313205224 startingPage "362" @default.
- W4313205224 abstract "Parathyroid cancer (PС) is a rare malignant neoplasm of the endocrine system, characterized by a severe course due to the development of life-threatening hypercalcemia. Despite a relatively high survival rate, recurrence occurs about half the time. The aggressive course of PС is associated with both local spread of the process and distant metastasis. With the exception of isolated cases, cytotoxic chemo- and radiotherapy are inefficacious, and treatment protocols have not been developed. Therefore the only effective way is the surgical removal of secondary lesions, which is not always technically feasible and is associated with a high risk of postoperative complications. The literature describes individual cases of successful use of targeted therapy, as well as immunotherapy in the form of therapeutic vaccination to induce an immune response against parathyroid hormone (PTH) and block immune checkpoint. A promising direction of study is the tumor immunoenvironment, which has both diagnostic and prognostic value in relation to the likelihood of the spread of the tumor process. In this review, we describe the main directions in the treatment of PC, including disseminated forms, the possibilities of immunotherapy will be considered in details." @default.
- W4313205224 created "2023-01-06" @default.
- W4313205224 creator A5002755280 @default.
- W4313205224 creator A5055970460 @default.
- W4313205224 creator A5060633744 @default.
- W4313205224 creator A5068946220 @default.
- W4313205224 creator A5083941941 @default.
- W4313205224 date "2022-12-28" @default.
- W4313205224 modified "2023-10-14" @default.
- W4313205224 title "Treatment of Parathyroid Cancer: Current Status and Near-Term Prospects" @default.
- W4313205224 cites W1540625678 @default.
- W4313205224 cites W1835750525 @default.
- W4313205224 cites W1971771058 @default.
- W4313205224 cites W1984545852 @default.
- W4313205224 cites W1992113941 @default.
- W4313205224 cites W1996430458 @default.
- W4313205224 cites W2009721316 @default.
- W4313205224 cites W2012090427 @default.
- W4313205224 cites W2016000348 @default.
- W4313205224 cites W2019967033 @default.
- W4313205224 cites W2021595079 @default.
- W4313205224 cites W2026027035 @default.
- W4313205224 cites W2029086221 @default.
- W4313205224 cites W2039829925 @default.
- W4313205224 cites W2060277294 @default.
- W4313205224 cites W2062871577 @default.
- W4313205224 cites W2064095945 @default.
- W4313205224 cites W2064454796 @default.
- W4313205224 cites W2070422397 @default.
- W4313205224 cites W2072535180 @default.
- W4313205224 cites W2077418105 @default.
- W4313205224 cites W2078599252 @default.
- W4313205224 cites W2091383172 @default.
- W4313205224 cites W2132057914 @default.
- W4313205224 cites W2137194796 @default.
- W4313205224 cites W2145949546 @default.
- W4313205224 cites W2150468893 @default.
- W4313205224 cites W2157565690 @default.
- W4313205224 cites W2165923318 @default.
- W4313205224 cites W2173934737 @default.
- W4313205224 cites W2287918349 @default.
- W4313205224 cites W2289439748 @default.
- W4313205224 cites W2310914079 @default.
- W4313205224 cites W2534471526 @default.
- W4313205224 cites W2597253561 @default.
- W4313205224 cites W2599486266 @default.
- W4313205224 cites W2624057382 @default.
- W4313205224 cites W2797859505 @default.
- W4313205224 cites W2896761970 @default.
- W4313205224 cites W2924837074 @default.
- W4313205224 cites W2945220277 @default.
- W4313205224 cites W2958922334 @default.
- W4313205224 cites W2981392087 @default.
- W4313205224 cites W2990089898 @default.
- W4313205224 cites W3009048917 @default.
- W4313205224 cites W3011706129 @default.
- W4313205224 cites W3013222031 @default.
- W4313205224 cites W3026327369 @default.
- W4313205224 cites W3088509180 @default.
- W4313205224 cites W3137914501 @default.
- W4313205224 cites W3174830628 @default.
- W4313205224 cites W3189153530 @default.
- W4313205224 cites W4211243636 @default.
- W4313205224 cites W4213295943 @default.
- W4313205224 cites W4241757164 @default.
- W4313205224 cites W4288058865 @default.
- W4313205224 cites W4362203951 @default.
- W4313205224 cites W94928566 @default.
- W4313205224 doi "https://doi.org/10.15690/vramn2132" @default.
- W4313205224 hasPublicationYear "2022" @default.
- W4313205224 type Work @default.
- W4313205224 citedByCount "0" @default.
- W4313205224 crossrefType "journal-article" @default.
- W4313205224 hasAuthorship W4313205224A5002755280 @default.
- W4313205224 hasAuthorship W4313205224A5055970460 @default.
- W4313205224 hasAuthorship W4313205224A5060633744 @default.
- W4313205224 hasAuthorship W4313205224A5068946220 @default.
- W4313205224 hasAuthorship W4313205224A5083941941 @default.
- W4313205224 hasConcept C121608353 @default.
- W4313205224 hasConcept C126322002 @default.
- W4313205224 hasConcept C143998085 @default.
- W4313205224 hasConcept C203014093 @default.
- W4313205224 hasConcept C22070199 @default.
- W4313205224 hasConcept C2777701055 @default.
- W4313205224 hasConcept C2778378633 @default.
- W4313205224 hasConcept C2779013556 @default.
- W4313205224 hasConcept C2781208988 @default.
- W4313205224 hasConcept C3019926457 @default.
- W4313205224 hasConcept C46699223 @default.
- W4313205224 hasConcept C509974204 @default.
- W4313205224 hasConcept C519063684 @default.
- W4313205224 hasConcept C71315377 @default.
- W4313205224 hasConcept C71924100 @default.
- W4313205224 hasConcept C8891405 @default.
- W4313205224 hasConceptScore W4313205224C121608353 @default.
- W4313205224 hasConceptScore W4313205224C126322002 @default.
- W4313205224 hasConceptScore W4313205224C143998085 @default.
- W4313205224 hasConceptScore W4313205224C203014093 @default.