FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313207622> ?p ?o ?g. }

• W4313207622 endingPage "1971" @default.
• W4313207622 startingPage "1956" @default.
• W4313207622 abstract "The importance of Hypericum L. species, being used in traditional medicine, in the scientific world is increasing day by day. Hypericum species are plants that have been used in the treatment of many diseases for a long time and have healing properties. In the current study, the essential oil compositions of Hypericum scabrum L. and H. ternatum Poulter collected from different localities in Turkey were determined by GC-MS/FID. In addition, their antioxidant, cytotoxic, and antimicrobial activities with their enzyme inhibitory potentials (cholinesterase, urease, tyrosinase, elastase, and collagenase) were investigated. Also, in vitro and in silico studies of the major components of the species have been carried out on the studied enzymes. It was determined that four H. scabrum samples mainly contained α-pinene (55.99%-62.80%) while three H. ternatum samples contained 2-methyloctane (9.45%-22.39%) and α-pinene (12.75%-33.08%). While H. scabrum essential oils possessed significant biological activity potential except for the antimicrobial activity, H. ternatum samples did not. All essential oil samples of H. scabrum exhibited a high cytotoxic effect (IC50 21.67 ± 0.34 to 34.67 ± 0.45 μg/mL) against colon cancer cell line (HT-29) and indicated higher acetyl-(Inhibiton% 83.30 ± 1.90 to 93.08 ± 1.04) and butyryl-cholinesterase (Inhibiton% 80.58 ± 1.19 to 93.28 ± 1.99) inhibitory activity than the standard compound, galantamine. Furthermore, all samples of H. scabrum showed high tyrosinase (Inhibiton% 69.00 ± 1.64 to 95.25 ± 1.42) and elastase (Inhibiton% 27.58 ± 0.34 to 36.69 ± 0.18) inhibitory effects. These biological activity results indicated that H. scabrum essential oil could be used in the cosmetic and pharmaceutical industries." @default.
• W4313207622 created "2023-01-06" @default.
• W4313207622 creator A5007913453 @default.
• W4313207622 creator A5008174910 @default.
• W4313207622 creator A5020947260 @default.
• W4313207622 creator A5032431899 @default.
• W4313207622 creator A5041903698 @default.
• W4313207622 creator A5044708846 @default.
• W4313207622 creator A5046996315 @default.
• W4313207622 creator A5070027906 @default.
• W4313207622 creator A5089299572 @default.
• W4313207622 date "2022-01-01" @default.
• W4313207622 modified "2023-09-30" @default.
• W4313207622 title "Determination of essential oil and biological activities of Hypericum ternatum Poulter and H. scabrum L. species collected from different localities: is H. scabrum an alternative to multifunctional species ST JOHN'S WORT (H. perforatum)?" @default.
• W4313207622 cites W1950814129 @default.
• W4313207622 cites W1966755772 @default.
• W4313207622 cites W1971048984 @default.
• W4313207622 cites W1985729602 @default.
• W4313207622 cites W1992544322 @default.
• W4313207622 cites W1996115167 @default.
• W4313207622 cites W2012991711 @default.
• W4313207622 cites W2024772121 @default.
• W4313207622 cites W2069123478 @default.
• W4313207622 cites W2076313217 @default.
• W4313207622 cites W2079756377 @default.
• W4313207622 cites W2083881141 @default.
• W4313207622 cites W2118233996 @default.
• W4313207622 cites W2123446590 @default.
• W4313207622 cites W2132629607 @default.
• W4313207622 cites W2147623497 @default.
• W4313207622 cites W2160521780 @default.
• W4313207622 cites W2531874273 @default.
• W4313207622 cites W2794515125 @default.
• W4313207622 cites W2899740973 @default.
• W4313207622 cites W3026734579 @default.
• W4313207622 cites W3043274053 @default.
• W4313207622 cites W3082426847 @default.
• W4313207622 cites W3187599014 @default.
• W4313207622 cites W80974976 @default.
• W4313207622 doi "https://doi.org/10.55730/1300-0527.3494" @default.
• W4313207622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/37621346" @default.
• W4313207622 hasPublicationYear "2022" @default.
• W4313207622 type Work @default.
• W4313207622 citedByCount "0" @default.
• W4313207622 crossrefType "journal-article" @default.
• W4313207622 hasAuthorship W4313207622A5007913453 @default.
• W4313207622 hasAuthorship W4313207622A5008174910 @default.
• W4313207622 hasAuthorship W4313207622A5020947260 @default.
• W4313207622 hasAuthorship W4313207622A5032431899 @default.
• W4313207622 hasAuthorship W4313207622A5041903698 @default.
• W4313207622 hasAuthorship W4313207622A5044708846 @default.
• W4313207622 hasAuthorship W4313207622A5046996315 @default.
• W4313207622 hasAuthorship W4313207622A5070027906 @default.
• W4313207622 hasAuthorship W4313207622A5089299572 @default.
• W4313207622 hasBestOaLocation W43132076221 @default.
• W4313207622 hasConcept C178790620 @default.
• W4313207622 hasConcept C185592680 @default.
• W4313207622 hasConcept C2777278459 @default.
• W4313207622 hasConcept C2778215561 @default.
• W4313207622 hasConcept C31903555 @default.
• W4313207622 hasConcept C4937899 @default.
• W4313207622 hasConcept C556039675 @default.
• W4313207622 hasConcept C59822182 @default.
• W4313207622 hasConcept C71924100 @default.
• W4313207622 hasConcept C86803240 @default.
• W4313207622 hasConceptScore W4313207622C178790620 @default.
• W4313207622 hasConceptScore W4313207622C185592680 @default.
• W4313207622 hasConceptScore W4313207622C2777278459 @default.
• W4313207622 hasConceptScore W4313207622C2778215561 @default.
• W4313207622 hasConceptScore W4313207622C31903555 @default.
• W4313207622 hasConceptScore W4313207622C4937899 @default.
• W4313207622 hasConceptScore W4313207622C556039675 @default.
• W4313207622 hasConceptScore W4313207622C59822182 @default.
• W4313207622 hasConceptScore W4313207622C71924100 @default.
• W4313207622 hasConceptScore W4313207622C86803240 @default.
• W4313207622 hasIssue "6" @default.
• W4313207622 hasLocation W43132076221 @default.
• W4313207622 hasLocation W43132076222 @default.
• W4313207622 hasOpenAccess W4313207622 @default.
• W4313207622 hasPrimaryLocation W43132076221 @default.
• W4313207622 hasRelatedWork W1990348080 @default.
• W4313207622 hasRelatedWork W2022813227 @default.
• W4313207622 hasRelatedWork W2031901208 @default.
• W4313207622 hasRelatedWork W2037554370 @default.
• W4313207622 hasRelatedWork W2095212420 @default.
• W4313207622 hasRelatedWork W2396822601 @default.
• W4313207622 hasRelatedWork W2783980601 @default.
• W4313207622 hasRelatedWork W3204827011 @default.
• W4313207622 hasRelatedWork W4317242125 @default.
• W4313207622 hasRelatedWork W2184514585 @default.
• W4313207622 hasVolume "46" @default.
• W4313207622 isParatext "false" @default.
• W4313207622 isRetracted "false" @default.
• W4313207622 workType "article" @default.