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- W4313208765 abstract "Aim & objectives: Current investigation was carried out to evaluate the expression of the miR-193, miR-122 and miR-155 and also lipid profile in antimony-susceptible and resistance patients with Cutaneous leishmaniasis. Methods: Lesion and blood samples were collected from 27 antimony-resistance and 27 antimony-susceptible patients. mRNA were extracted and synthase to the cDNA using commercial kits according to the manufactures guideline. The expression of miR-193, miR-122 and miR-155 were evaluated using Real Time PCR technique. The serum lipid profiles were measured by enzymatic methods. Results: Our results indicated that the expression of the miR-193, miR-122 and miR-155 were significantly higher in antimony-susceptible patients. The results of current study indicated that downregulation of miRNAs are coupled with low serum LDL-C and triglyceride. Interpretation & Conclusion: It can be concluded that downregulation of miRNAs and decrease in lipid levels may be one of the mechanisms of parasite to escape from host immune system." @default.
- W4313208765 created "2023-01-06" @default.
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- W4313208765 date "2022-01-01" @default.
- W4313208765 modified "2023-09-30" @default.
- W4313208765 title "The Expression of the miR-193, miR-122 and miR-155 profiling and evaluation the serum lipid in antimony-susceptible and resistance patients with Cutaneous Leishmaniasis" @default.
- W4313208765 doi "https://doi.org/10.4103/0972-9062.328816" @default.
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