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- W4313208976 abstract "Background & objectives: In America, of the 44 species of Anopheles, nine are main vectors of malaria and of these, genetic information exists for seven. Hence, this study sought to know at Americas level the gene flow and diversity of the seven principal vectors of malaria at Americas level. Methods: For the seven species and from the sequences of the mitochondrial cytochrome c oxidase I (COI) gene obtained from the GenBank and Bold System, genetic analyzes of populations and genetic structure were performed. Besides obtaining for all of them the haplotype networks and phylogenetic trees. Results: Forthe seven species, 1,440 sequences were analyzed and 519 haplotypes were detected. The Hd and π values were higher within a continental context than by countries. Neutrality tests indicated positive and negative values with most of these being significant (p < 0.05). Phylogenetic analyses for all the species recovered three clades with no geographic pattern among these. Interpretation & conclusion: Studies suggest that native species of Anopheles from the Americas have greater haplotype diversity and low genetic differentiation due to the lack of physical barriers to impede gene flow among these populations. Moreover, all the species are interconnected by roadways. All this complicates the epidemiological picture of malaria in the Americas." @default.
- W4313208976 created "2023-01-06" @default.
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- W4313208976 date "2022-01-01" @default.
- W4313208976 modified "2023-10-01" @default.
- W4313208976 title "Dispersion routes of the main vectors of human malaria in the Americas: Genetic evidence from the mitochondrial COI gene" @default.
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- W4313208976 doi "https://doi.org/10.4103/0972-9062.361173" @default.
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