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- W4313209364 abstract "It is known that the presence of microorganisms with probiotic properties protects the body from pathogenic bacteria. The classification of symbiotic microorganisms living in the human gastrointestinal tract is constantly changing. Probiotics do not form colonies in the intestine, therefore, to obtain a long-term positive effect, the concentrations of probiotic strains in the intestine should reach a level of at least 10⁸ CFU/ml and remain so for a long time. The biotechnology of designing probiotic drugs is based on the isolation of probiotic strains of microbes from the intestines of a healthy individual. This is the basis for a new promising direction in practical medicine — the preparation of autoprobiotics used for the treatment and prevention of various diseases. The recommended effective daily dose of probiotic should be 10⁸–10⁹ CFU, but the dose may vary depending on the probiotic strain and the pharmaceutical form. The preservation of the viability of bacteria in the required amount until the end of the drug shelf life is also crucial for its effective use. It is assumed that auto-strains of probiotics in identical doses will be effective as well." @default.
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- W4313209364 date "2022-11-30" @default.
- W4313209364 modified "2023-09-27" @default.
- W4313209364 title "Selection of an effective dose of autologous probiotics for patients in the rehabilitation period" @default.
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- W4313209364 doi "https://doi.org/10.33920/med-14-2212-08" @default.
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