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• W4313223602 abstract "Abstract Purpose: To develop and validate a new multivariable prediction model to estimate risk of abnormal vault after EVO Implantable Collamer Lens (EVO-ICL) implantation using the preoperative parameters. Methods: This retrospective study comprised 282 eyes of 143patients who underwent EVO-ICL surgery between May 2021 and April 2022. We measured preoperative parameters and vaults in 1 week after the operation using swept-source optical coherence tomography (SS-OCT). Risk factors for abnormal vault were determined by univariate and multivariate logistic regression analyses, and a nomogram was developed to forecast the probability of abnormal vault after EVO-ICL implantation. We assessed the performance of nomogram in terms of discrimination and calibration, including concordance index (C-index), area under the curve (AUC), and decision curve analysis (DCA). Bootstrap resampling was used as an internal verification method. Results: The logistic regression analysis revealed the independent risk factors for abnormal vault were WTW, ACA, pupil size, and ICL-width, all of them were used to establish a nomogram to predict the risk of abnormal vault. The C-indexes and AUC were 0.669 (95%CI, 0.605, 0.733). The calibration curves of the nomogram showed relatively small bias from the reference line, implicating an acceptable degree of confidence. The DCA indicates the potential clinical significance of the nomogram. Conclusion: We developed a new multivariable prediction model to estimate risk of abnormal vault. The model shows good prediction effect and can provide assistance for clinical decision of ICL size." @default.
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• W4313223602 date "2022-12-28" @default.
• W4313223602 modified "2023-10-18" @default.
• W4313223602 title "Development and Validation of a New Multivariable Prediction Model to Estimate Risk of Abnormal Vault" @default.
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• W4313223602 doi "https://doi.org/10.21203/rs.3.rs-2365371/v1" @default.
• W4313223602 hasPublicationYear "2022" @default.
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