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- W4313225757 abstract "GJF 처리된 PANC-1 인간 췌장암 세포의 증식이 농도의존적으로 억제되었고, 이는 GJF에 의한 세포주기 S기에서의 세포 축적으로 인한 세포주기 정지 유도 및 세포주기 조절단백질의 과도한 발현 저해 활성과 관련이 있음을 확인하였다. 또한 GJF의 함유 성분인 geniposide 및 4,5-dicaffeoylquinic acid가 췌장암 세포에 대해서 GJF와 유사한 증식억제활성을 나타내었다. 이와 같이, GJF의 췌장암 세포주기 제어 및 증식억제결과와 그 활성성분으로 geniposide 및 폴리페놀인 4,5-dicaffeoylquinic acid를 제시함으로써 GJF의 항암 활성에 대한 기초자료로 활용될 수 있을 것으로 생각된다." @default.
- W4313225757 created "2023-01-06" @default.
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- W4313225757 date "2022-10-31" @default.
- W4313225757 modified "2023-10-17" @default.
- W4313225757 title "Cell cycle arrest by Gardenia jasminoides fruit and anti-proliferative activity by its active components in pancreatic cancer PANC-1 cells" @default.
- W4313225757 doi "https://doi.org/10.9721/kjfst.2022.54.5.555" @default.
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