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- W4313229625 endingPage "350" @default.
- W4313229625 startingPage "271" @default.
- W4313229625 abstract "Microbial virulence showcases an excellent model for adaptive changes that enable an organism to survive and proliferate in a hostile environment and exploit host resources to its own benefit. In Staphylococcus aureus, an opportunistic pathogen of the human host, known for the diversity of the disease conditions it inflicts and the rapid evolution of antibiotic resistance, virulence is a consequence of having a highly plastic genome that is amenable to quick reprogramming and the ability to express a diverse arsenal of virulence factors. Virulence factors that are secreted to the host milieu effectively manipulate the host conditions to favor bacterial survival and growth. They assist in colonization, nutrient acquisition, immune evasion, and systemic spread. The structural and functional characteristics of the secreted virulence proteins have been shaped to assist S. aureus in thriving and disseminating effectively within the host environment and exploiting the host resources to its best benefit. With the aim of highlighting the importance of secreted virulence proteins in bacterial virulence, the present chapter provides a comprehensive account of the role of the major secreted proteins of S. aureus in orchestrating its virulence in the human host." @default.
- W4313229625 created "2023-01-06" @default.
- W4313229625 creator A5026925461 @default.
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- W4313229625 creator A5040596483 @default.
- W4313229625 creator A5044489113 @default.
- W4313229625 creator A5058261704 @default.
- W4313229625 date "2023-01-01" @default.
- W4313229625 modified "2023-10-01" @default.
- W4313229625 title "Secretory proteins in the orchestration of microbial virulence: The curious case of Staphylococcus aureus" @default.
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