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• W4313231194 abstract "Abstract Neuroimaging data is complex and high-dimensional that poses challenges for machine learning (ML) applications. Of varieties of reasons contributing on accuracy decoding, variable feature selection is one of crucial steps for determining target feature in data analysis, especially in the context of neuroimaging studies where the number of features is often much larger than the number of observations. Therefore, optimization of feature selection from such high-dimensional neuroimaging data has been challenging using conventional ML algorithms. Here, we introduce an efficient ML package incorporating a forward variable selection (FVS) algorithm that optimizes the identification of features for both classification and regression models. In our framework, the best ML model and feature pairs that explain the inputs can be automatically determined. Moreover, the toolbox can be executed in a parallel environment for efficient computation. The parallelized FVS algorithm iteratively selects the best feature pair compared against the previous steps to maximize the predictive performance. The FVS algorithm evaluates the goodness-of-fit across different models using the k-fold cross validation and identifies the best subset of features based on a pre-defined criterion for each model. Furthermore, the hyperparameters of each ML model are optimized at each forward iteration. A final outcome highlights an optimized number of selected features (brain regions of interest) with decoding accuracies. Using our pipeline, we examined the effectiveness of our toolbox on an existing neuroimaging (structural MRI) dataset. Compared ML models with and without FVS approach, we demonstrate that the FVS significantly improved the accuracy of the ML algorithm over the counterpart model without FVS. Furthermore, we confirmed the use of parallel computation considerably reduced the computational burden for the high-dimensional MRI data. This oFVSD toolbox efficiently and effectively improves the performance of both classification and regression models on neuroimaging data and should be applicable to many other neuroimaging data and more. This Python package is open-source and freely available, making it a useful toolbox for neuroimaging communities seeking improvement of decoding accuracy for their datasets." @default.
• W4313231194 created "2023-01-06" @default.
• W4313231194 creator A5039776578 @default.
• W4313231194 creator A5040997156 @default.
• W4313231194 creator A5043380578 @default.
• W4313231194 date "2022-12-25" @default.
• W4313231194 modified "2023-10-02" @default.
• W4313231194 title "oFVSD: A Python package of optimized forward variable selection decoder for high-dimensional neuroimaging data" @default.
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• W4313231194 doi "https://doi.org/10.1101/2022.12.25.521906" @default.
• W4313231194 hasPublicationYear "2022" @default.
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