FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313231518> ?p ?o ?g. }

• W4313231518 endingPage "212" @default.
• W4313231518 startingPage "201" @default.
• W4313231518 abstract "Copper (Cu) is a trace element necessary for the growth and development of all living organisms, and is the third most abundant trace metal in the body after iron and zinc. Copper is essential for maintaining the life processes in all living cells, because several copper-dependent enzymes play an important role in key physiological processes like cellular respiration, oxygen radical scavenging, the transport of iron and neurotransmitter synthesis. Maintaining copper homeostasis implies maintaining the constancy of copper levels in the cells and fluids throughout the body, in order to support the enzymes and other factors that underlie normal life processes. Therefore, living organisms have developed complex mechanisms for maintaining their physiological copper level, because an excess copper level can be toxic for the cells. In the cell, copper homeostasis is controlled by a network of copper-binding proteins and transporters. Furthermore, copper uptake is mediated by the membrane transporter CTR1 and CTR2 proteins. In the cytoplasm, it is bound to a unique group of metallochaperones (ATOX1, CCS COX17) and transported to different cell compartments, where it is linked to the recipient proteins. The Cu-transporting ATPases (ATP7A and ATP7B) are responsible for transferring copper into the Golgi apparatus, where the copper is added to the active sites of enzymes, and it is also directed onto the path of excess cellular copper removal to prevent the occurrence of toxicity." @default.
• W4313231518 created "2023-01-06" @default.
• W4313231518 creator A5014184670 @default.
• W4313231518 creator A5021524676 @default.
• W4313231518 creator A5023091122 @default.
• W4313231518 creator A5029888369 @default.
• W4313231518 creator A5031376678 @default.
• W4313231518 creator A5065270429 @default.
• W4313231518 date "2022-12-06" @default.
• W4313231518 modified "2023-10-14" @default.
• W4313231518 title "Molecular Mechanisms of Cellular Copper Homeostasis in Mammals" @default.
• W4313231518 cites W1496283406 @default.
• W4313231518 cites W1534180163 @default.
• W4313231518 cites W1847684025 @default.
• W4313231518 cites W1968428170 @default.
• W4313231518 cites W1969665448 @default.
• W4313231518 cites W1980129971 @default.
• W4313231518 cites W1993651887 @default.
• W4313231518 cites W2023618834 @default.
• W4313231518 cites W2038955988 @default.
• W4313231518 cites W2040964500 @default.
• W4313231518 cites W2049105010 @default.
• W4313231518 cites W2050609818 @default.
• W4313231518 cites W2060892573 @default.
• W4313231518 cites W2063157862 @default.
• W4313231518 cites W2063623021 @default.
• W4313231518 cites W2076234140 @default.
• W4313231518 cites W2103420271 @default.
• W4313231518 cites W2109928864 @default.
• W4313231518 cites W2111148351 @default.
• W4313231518 cites W2118480909 @default.
• W4313231518 cites W2122373849 @default.
• W4313231518 cites W2126727119 @default.
• W4313231518 cites W2126898944 @default.
• W4313231518 cites W2132688773 @default.
• W4313231518 cites W2152105575 @default.
• W4313231518 cites W2337379315 @default.
• W4313231518 cites W2340479756 @default.
• W4313231518 cites W2347202125 @default.
• W4313231518 cites W2590237199 @default.
• W4313231518 cites W2728934083 @default.
• W4313231518 cites W2981918029 @default.
• W4313231518 cites W3088376528 @default.
• W4313231518 doi "https://doi.org/10.3409/fb_70-4.23" @default.
• W4313231518 hasPublicationYear "2022" @default.
• W4313231518 type Work @default.
• W4313231518 citedByCount "2" @default.
• W4313231518 countsByYear W43132315182023 @default.
• W4313231518 crossrefType "journal-article" @default.
• W4313231518 hasAuthorship W4313231518A5014184670 @default.
• W4313231518 hasAuthorship W4313231518A5021524676 @default.
• W4313231518 hasAuthorship W4313231518A5023091122 @default.
• W4313231518 hasAuthorship W4313231518A5029888369 @default.
• W4313231518 hasAuthorship W4313231518A5031376678 @default.
• W4313231518 hasAuthorship W4313231518A5065270429 @default.
• W4313231518 hasBestOaLocation W43132315181 @default.
• W4313231518 hasConcept C104317684 @default.
• W4313231518 hasConcept C119062480 @default.
• W4313231518 hasConcept C12554922 @default.
• W4313231518 hasConcept C149011108 @default.
• W4313231518 hasConcept C1491633281 @default.
• W4313231518 hasConcept C178790620 @default.
• W4313231518 hasConcept C181199279 @default.
• W4313231518 hasConcept C185592680 @default.
• W4313231518 hasConcept C23265538 @default.
• W4313231518 hasConcept C2777106986 @default.
• W4313231518 hasConcept C2777581567 @default.
• W4313231518 hasConcept C2778404011 @default.
• W4313231518 hasConcept C2779736553 @default.
• W4313231518 hasConcept C2991729501 @default.
• W4313231518 hasConcept C544778455 @default.
• W4313231518 hasConcept C55493867 @default.
• W4313231518 hasConcept C63645605 @default.
• W4313231518 hasConcept C86803240 @default.
• W4313231518 hasConcept C95444343 @default.
• W4313231518 hasConceptScore W4313231518C104317684 @default.
• W4313231518 hasConceptScore W4313231518C119062480 @default.
• W4313231518 hasConceptScore W4313231518C12554922 @default.
• W4313231518 hasConceptScore W4313231518C149011108 @default.
• W4313231518 hasConceptScore W4313231518C1491633281 @default.
• W4313231518 hasConceptScore W4313231518C178790620 @default.
• W4313231518 hasConceptScore W4313231518C181199279 @default.
• W4313231518 hasConceptScore W4313231518C185592680 @default.
• W4313231518 hasConceptScore W4313231518C23265538 @default.
• W4313231518 hasConceptScore W4313231518C2777106986 @default.
• W4313231518 hasConceptScore W4313231518C2777581567 @default.
• W4313231518 hasConceptScore W4313231518C2778404011 @default.
• W4313231518 hasConceptScore W4313231518C2779736553 @default.
• W4313231518 hasConceptScore W4313231518C2991729501 @default.
• W4313231518 hasConceptScore W4313231518C544778455 @default.
• W4313231518 hasConceptScore W4313231518C55493867 @default.
• W4313231518 hasConceptScore W4313231518C63645605 @default.
• W4313231518 hasConceptScore W4313231518C86803240 @default.
• W4313231518 hasConceptScore W4313231518C95444343 @default.
• W4313231518 hasIssue "4" @default.
• W4313231518 hasLocation W43132315181 @default.
• W4313231518 hasLocation W43132315182 @default.
• W4313231518 hasOpenAccess W4313231518 @default.

• next