Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313233406> ?p ?o ?g. }
- W4313233406 abstract "Neutrophil elastase (NE) plays a key role in chronic inflammation and acute responses to infection and injury. Effective disease interventions thus call for precise identification of NE to aid the clinical treatment of such diseases. However, the detection process suffers from the interference of structural changes of NE. Herein, we introduce a molecular probe with high biocompatibility to overcome the interference, which was achieved by combining theoretical calculations and experimental studies, that permits highly specific and sensitive detection of NE in cells and in vivo. The upregulated NE accumulation was specifically measured in inflammation by ratiometric photoacoustic and near-infrared fluorescence imaging, providing a new method for developing more specific fluorogenic probes for other enzymes." @default.
- W4313233406 created "2023-01-06" @default.
- W4313233406 creator A5000613792 @default.
- W4313233406 creator A5023541518 @default.
- W4313233406 creator A5044516301 @default.
- W4313233406 creator A5046207199 @default.
- W4313233406 creator A5059901181 @default.
- W4313233406 creator A5076055914 @default.
- W4313233406 creator A5085433059 @default.
- W4313233406 date "2023-01-20" @default.
- W4313233406 modified "2023-10-17" @default.
- W4313233406 title "A Biocompatible Probe for the Detection of Neutrophil Elastase Free from the Interference of Structural Changes and Its Application to Ratiometric Photoacoustic Imaging In Vivo" @default.
- W4313233406 cites W1977096237 @default.
- W4313233406 cites W1981047925 @default.
- W4313233406 cites W2000106654 @default.
- W4313233406 cites W2004121149 @default.
- W4313233406 cites W2005334224 @default.
- W4313233406 cites W2006786912 @default.
- W4313233406 cites W2012099137 @default.
- W4313233406 cites W2030964111 @default.
- W4313233406 cites W2032227357 @default.
- W4313233406 cites W2034808365 @default.
- W4313233406 cites W2036361783 @default.
- W4313233406 cites W2045723131 @default.
- W4313233406 cites W2053142936 @default.
- W4313233406 cites W2054555135 @default.
- W4313233406 cites W2062265555 @default.
- W4313233406 cites W2072322888 @default.
- W4313233406 cites W2075503331 @default.
- W4313233406 cites W2076881902 @default.
- W4313233406 cites W2078726413 @default.
- W4313233406 cites W2094956351 @default.
- W4313233406 cites W2098888044 @default.
- W4313233406 cites W2126392408 @default.
- W4313233406 cites W2132363144 @default.
- W4313233406 cites W2137522692 @default.
- W4313233406 cites W2138694950 @default.
- W4313233406 cites W2149302140 @default.
- W4313233406 cites W2155551630 @default.
- W4313233406 cites W2161179716 @default.
- W4313233406 cites W2335370064 @default.
- W4313233406 cites W2337585522 @default.
- W4313233406 cites W2484448248 @default.
- W4313233406 cites W2569658671 @default.
- W4313233406 cites W2751110354 @default.
- W4313233406 cites W2769277374 @default.
- W4313233406 cites W2777371746 @default.
- W4313233406 cites W2925268815 @default.
- W4313233406 cites W2946216397 @default.
- W4313233406 cites W2949216521 @default.
- W4313233406 cites W2967255981 @default.
- W4313233406 cites W2969560376 @default.
- W4313233406 cites W3004238134 @default.
- W4313233406 cites W3011351825 @default.
- W4313233406 cites W3037842676 @default.
- W4313233406 cites W3043358366 @default.
- W4313233406 cites W3100844675 @default.
- W4313233406 cites W3103527516 @default.
- W4313233406 cites W3124962132 @default.
- W4313233406 cites W3157539725 @default.
- W4313233406 cites W3157599532 @default.
- W4313233406 cites W3160411478 @default.
- W4313233406 cites W4205235493 @default.
- W4313233406 cites W4224308513 @default.
- W4313233406 cites W4236973945 @default.
- W4313233406 cites W4242087435 @default.
- W4313233406 cites W4243606508 @default.
- W4313233406 cites W4246300392 @default.
- W4313233406 doi "https://doi.org/10.1002/anie.202217508" @default.
- W4313233406 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36578174" @default.
- W4313233406 hasPublicationYear "2023" @default.
- W4313233406 type Work @default.
- W4313233406 citedByCount "5" @default.
- W4313233406 countsByYear W43132334062023 @default.
- W4313233406 crossrefType "journal-article" @default.
- W4313233406 hasAuthorship W4313233406A5000613792 @default.
- W4313233406 hasAuthorship W4313233406A5023541518 @default.
- W4313233406 hasAuthorship W4313233406A5044516301 @default.
- W4313233406 hasAuthorship W4313233406A5046207199 @default.
- W4313233406 hasAuthorship W4313233406A5059901181 @default.
- W4313233406 hasAuthorship W4313233406A5076055914 @default.
- W4313233406 hasAuthorship W4313233406A5085433059 @default.
- W4313233406 hasConcept C120665830 @default.
- W4313233406 hasConcept C121332964 @default.
- W4313233406 hasConcept C12554922 @default.
- W4313233406 hasConcept C1318750 @default.
- W4313233406 hasConcept C136229726 @default.
- W4313233406 hasConcept C136339569 @default.
- W4313233406 hasConcept C150903083 @default.
- W4313233406 hasConcept C171250308 @default.
- W4313233406 hasConcept C178790620 @default.
- W4313233406 hasConcept C181199279 @default.
- W4313233406 hasConcept C185592680 @default.
- W4313233406 hasConcept C192562407 @default.
- W4313233406 hasConcept C203014093 @default.
- W4313233406 hasConcept C207001950 @default.
- W4313233406 hasConcept C2776914184 @default.
- W4313233406 hasConcept C2777230088 @default.
- W4313233406 hasConcept C2781044401 @default.
- W4313233406 hasConcept C29331040 @default.