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- W4313233455 abstract "Geranylgeranyl diphosphate synthase (GGDPS), an enzyme in the isoprenoid biosynthesis pathway, is responsible for the production of geranylgeranyl pyrophosphate (GGPP) used for protein geranylgeranylation. Dysregulation of GGDPS expression and/or activity is implicated in the pathophysiology of type 2 diabetes, liver disease, pulmonary disease and several malignancies. GGDPS inhibitors have promising efficacy in preclinical models of malignancy and pulmonary fibrosis." @default.
- W4313233455 created "2023-01-06" @default.
- W4313233455 date "2023-01-01" @default.
- W4313233455 modified "2023-10-14" @default.
- W4313233455 doi "https://doi.org/10.1002/ctm2.v13.1" @default.
- W4313233455 hasPublicationYear "2023" @default.
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