Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313236104> ?p ?o ?g. }
- W4313236104 abstract "Long noncoding ribonucleic acids (RNAs; LncRNAs) endowed with both protein-coding and noncoding functions are referred to as 'dual functional lncRNAs'. Recently, dual functional lncRNAs have been intensively studied and identified as involved in various fundamental cellular processes. However, apart from time-consuming and cell-type-specific experiments, there is virtually no in silico method for predicting the identity of dual functional lncRNAs. Here, we developed a deep-learning model with a multi-head self-attention mechanism, LncReader, to identify dual functional lncRNAs. Our data demonstrated that LncReader showed multiple advantages compared to various classical machine learning methods using benchmark datasets from our previously reported cncRNAdb project. Moreover, to obtain independent in-house datasets for robust testing, mass spectrometry proteomics combined with RNA-seq and Ribo-seq were applied in four leukaemia cell lines, which further confirmed that LncReader achieved the best performance compared to other tools. Therefore, LncReader provides an accurate and practical tool that enables fast dual functional lncRNA identification." @default.
- W4313236104 created "2023-01-06" @default.
- W4313236104 creator A5016343304 @default.
- W4313236104 creator A5027970420 @default.
- W4313236104 creator A5037036377 @default.
- W4313236104 creator A5039870429 @default.
- W4313236104 creator A5045347655 @default.
- W4313236104 creator A5056356646 @default.
- W4313236104 creator A5058200311 @default.
- W4313236104 creator A5062195339 @default.
- W4313236104 creator A5065926780 @default.
- W4313236104 creator A5068017226 @default.
- W4313236104 creator A5070571727 @default.
- W4313236104 creator A5080174368 @default.
- W4313236104 creator A5080366878 @default.
- W4313236104 date "2022-12-27" @default.
- W4313236104 modified "2023-10-14" @default.
- W4313236104 title "LncReader: identification of dual functional long noncoding RNAs using a multi-head self-attention mechanism" @default.
- W4313236104 cites W1553436411 @default.
- W4313236104 cites W1988790447 @default.
- W4313236104 cites W2005125317 @default.
- W4313236104 cites W2007439698 @default.
- W4313236104 cites W2017328537 @default.
- W4313236104 cites W2020678193 @default.
- W4313236104 cites W2026433130 @default.
- W4313236104 cites W2035031476 @default.
- W4313236104 cites W2048194168 @default.
- W4313236104 cites W2052503008 @default.
- W4313236104 cites W2055214702 @default.
- W4313236104 cites W2070777085 @default.
- W4313236104 cites W2073324553 @default.
- W4313236104 cites W2085220756 @default.
- W4313236104 cites W2086561953 @default.
- W4313236104 cites W2102278945 @default.
- W4313236104 cites W2104005232 @default.
- W4313236104 cites W2117977572 @default.
- W4313236104 cites W2123296798 @default.
- W4313236104 cites W2126187451 @default.
- W4313236104 cites W2156125289 @default.
- W4313236104 cites W2259938310 @default.
- W4313236104 cites W2337562960 @default.
- W4313236104 cites W2538320152 @default.
- W4313236104 cites W2544360569 @default.
- W4313236104 cites W2567665210 @default.
- W4313236104 cites W2593488635 @default.
- W4313236104 cites W2607796168 @default.
- W4313236104 cites W2615786037 @default.
- W4313236104 cites W2761249484 @default.
- W4313236104 cites W2886900083 @default.
- W4313236104 cites W2890617507 @default.
- W4313236104 cites W2898598946 @default.
- W4313236104 cites W2899760200 @default.
- W4313236104 cites W2900836409 @default.
- W4313236104 cites W2914164958 @default.
- W4313236104 cites W2914698725 @default.
- W4313236104 cites W2944606734 @default.
- W4313236104 cites W2949674037 @default.
- W4313236104 cites W2950063384 @default.
- W4313236104 cites W2954519497 @default.
- W4313236104 cites W2962975498 @default.
- W4313236104 cites W3000568989 @default.
- W4313236104 cites W3033852357 @default.
- W4313236104 cites W3082320051 @default.
- W4313236104 cites W3090569323 @default.
- W4313236104 cites W312531056 @default.
- W4313236104 cites W3125963888 @default.
- W4313236104 cites W3129839469 @default.
- W4313236104 cites W3136918052 @default.
- W4313236104 cites W3139265997 @default.
- W4313236104 cites W3174855653 @default.
- W4313236104 cites W3209678692 @default.
- W4313236104 cites W3217454473 @default.
- W4313236104 cites W4200439253 @default.
- W4313236104 cites W4294811379 @default.
- W4313236104 doi "https://doi.org/10.1093/bib/bbac579" @default.
- W4313236104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36575567" @default.
- W4313236104 hasPublicationYear "2022" @default.
- W4313236104 type Work @default.
- W4313236104 citedByCount "2" @default.
- W4313236104 countsByYear W43132361042023 @default.
- W4313236104 crossrefType "journal-article" @default.
- W4313236104 hasAuthorship W4313236104A5016343304 @default.
- W4313236104 hasAuthorship W4313236104A5027970420 @default.
- W4313236104 hasAuthorship W4313236104A5037036377 @default.
- W4313236104 hasAuthorship W4313236104A5039870429 @default.
- W4313236104 hasAuthorship W4313236104A5045347655 @default.
- W4313236104 hasAuthorship W4313236104A5056356646 @default.
- W4313236104 hasAuthorship W4313236104A5058200311 @default.
- W4313236104 hasAuthorship W4313236104A5062195339 @default.
- W4313236104 hasAuthorship W4313236104A5065926780 @default.
- W4313236104 hasAuthorship W4313236104A5068017226 @default.
- W4313236104 hasAuthorship W4313236104A5070571727 @default.
- W4313236104 hasAuthorship W4313236104A5080174368 @default.
- W4313236104 hasAuthorship W4313236104A5080366878 @default.
- W4313236104 hasConcept C104317684 @default.
- W4313236104 hasConcept C105795698 @default.
- W4313236104 hasConcept C111472728 @default.
- W4313236104 hasConcept C116834253 @default.
- W4313236104 hasConcept C124952713 @default.
- W4313236104 hasConcept C13280743 @default.