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• W4313236445 abstract "For the diagnosis of bone marrow edema (BME), spectral computed tomography (CT) has emerged as a promising technique.To study the different performances of spectral CT in the diagnosis of vertebral BME in young and middle-aged versus elderly patients.Magnetic resonance imaging (MRI) was used as the gold standard. To determine the existence of BME, spectral CT color-coded images of the vertebral bodies of 82 patients with vertebral compression fractures (VCFs) were visually inspected. A quantitative analysis of the spectral CT vertebral water concentration in the diagnosis of BME was performed using a receiver operating characteristic (ROC) curve. Patients were divided into two groups for comparison: the young and middle-aged group; and the elderly group.The sensitivity and specificity for visual assessment were 83.7% and 98.3%, respectively, in the young and middle-aged group and 96.8% and 98.2%, respectively, in the elderly group. The elderly group had a higher sensitivity than the young and middle-aged group (P < 0.05). With a threshold of 1046.2 mg/cm3, the ROC curve for the young and middle-aged group displayed an area under the curve (AUC) of 0.870, sensitivity of 86.0%, and specificity of 81.4%. The threshold of 1031.4 mg/cm3 yielded a sensitivity of 95.2% and a specificity of 98.4%, and the AUC of the elderly group was 0.997. The elderly group had a higher level of specificity than the young and middle-aged group (P < 0.05).Spectral CT can reliably diagnose BME in VCFs, and it performs better in elderly people than in young and middle-aged people." @default.
• W4313236445 created "2023-01-06" @default.
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• W4313236445 date "2022-12-27" @default.
• W4313236445 modified "2023-10-16" @default.
• W4313236445 title "Visual assessment and quantitative analysis of bone marrow edema in young and middle-aged versus elderly patients with vertebral compression fracture by spectral CT" @default.
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• W4313236445 doi "https://doi.org/10.1177/02841851221146977" @default.
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