Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313236534> ?p ?o ?g. }
Showing items 1 to 51 of
51
with 100 items per page.
- W4313236534 endingPage "2001" @default.
- W4313236534 startingPage "1995" @default.
- W4313236534 abstract "Objective: To determine the accuracy of pooled specimens from multiple individuals for detection of infection with Chlamydia trachomatis. Methods: By April 2022, PubMed and Embase searched relevant studies published in peer-reviewed journals. The QUADAS-2 scale of a quality assessment tool was used to assess the quality of the studies. A curve of summary receiver operating characteristic was applied as a comprehensive assessment of diagnosed accuracy. A bivariate mixed-effects model was used for overall value merging in sensitivity and specificity. In addition, the subgroup analyses regarding sample type, testing method, and the number of samples per pool were performed. Results: A total of 14 846 subjects were included in the analysis. Three studies were from the United States, three from Canada, three from Denmark, two from Lithuania, two from India, two from the Netherlands, and one from Australia, Russia, and Singapore. Compared with the individual specimens, the pooled specimens of multiple individuals had an overall sensitivity of 0.98 (95%CI: 0.97-0.99) and specificity of 1.00 (95%CI: 1.00-1.00) for the detection of Chlamydia trachomatis. Results from the subgroup showed that the overall sensitivity of ligase chain reaction was significantly higher than that of PCR in the diagnosis of pooled samples. Conclusion: It is concluded from the published studies that the pooled specimens were substantially consistent with the single specimens in detecting infection with Chlamydia trachomatis.目的： 对不同个体的样本混合后检测生殖道沙眼衣原体感染的准确性研究进行Meta分析。 方法： 通过PubMed和Embase数据库收集2022年4月之前发表的混合不同个体的样本检测生殖道沙眼衣原体感染准确性的相关文献。采用质量评价工具QUADAS-2量表进行文献质量评价。利用综合受试者工作特征曲线评估研究间的阈值效应并计算曲线下面积。采用双变量混合效应模型对不同个体的样本混合后诊断生殖道沙眼衣原体感染的灵敏度及特异度进行Meta分析，并进一步根据纳入文献中样本类型、检测技术、混合样本数量进行亚组分析。 结果： 纳入的18篇文献共调查人数14 846例，其中3篇来自美国，3篇来自加拿大，3篇来自丹麦，2篇来自立陶宛，2篇来自印度，2篇来自荷兰，来自澳大利亚、俄罗斯和新加坡各1篇。通过数据合并分析得到不同个体混合检测对于生殖道沙眼衣原体感染的总体灵敏度为0.98（95%CI：0.97~0.99），总体特异度为1.00（95%CI：1.00~1.00）。亚组分析显示，连接酶链反应技术诊断混合样本的合并灵敏度显著高于PCR技术。 结论： 基于发表研究可见，与单个个体检测结果相比，混合不同个体的样本检测用于生殖道沙眼衣原体感染的检测具有较高的一致性。." @default.
- W4313236534 created "2023-01-06" @default.
- W4313236534 creator A5004577901 @default.
- W4313236534 creator A5062845331 @default.
- W4313236534 date "2022-12-10" @default.
- W4313236534 modified "2023-09-28" @default.
- W4313236534 title "[Accuracy of pooling specimens from different individuals in the detection of genital Chlamydia trachomatis infection: a Meta analysis]." @default.
- W4313236534 doi "https://doi.org/10.3760/cma.j.cn112338-20220531-00484" @default.
- W4313236534 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36572475" @default.
- W4313236534 hasPublicationYear "2022" @default.
- W4313236534 type Work @default.
- W4313236534 citedByCount "0" @default.
- W4313236534 crossrefType "journal-article" @default.
- W4313236534 hasAuthorship W4313236534A5004577901 @default.
- W4313236534 hasAuthorship W4313236534A5062845331 @default.
- W4313236534 hasConcept C126322002 @default.
- W4313236534 hasConcept C203014093 @default.
- W4313236534 hasConcept C2777391075 @default.
- W4313236534 hasConcept C2780122209 @default.
- W4313236534 hasConcept C29456083 @default.
- W4313236534 hasConcept C58471807 @default.
- W4313236534 hasConcept C71924100 @default.
- W4313236534 hasConcept C95190672 @default.
- W4313236534 hasConceptScore W4313236534C126322002 @default.
- W4313236534 hasConceptScore W4313236534C203014093 @default.
- W4313236534 hasConceptScore W4313236534C2777391075 @default.
- W4313236534 hasConceptScore W4313236534C2780122209 @default.
- W4313236534 hasConceptScore W4313236534C29456083 @default.
- W4313236534 hasConceptScore W4313236534C58471807 @default.
- W4313236534 hasConceptScore W4313236534C71924100 @default.
- W4313236534 hasConceptScore W4313236534C95190672 @default.
- W4313236534 hasIssue "12" @default.
- W4313236534 hasLocation W43132365341 @default.
- W4313236534 hasOpenAccess W4313236534 @default.
- W4313236534 hasPrimaryLocation W43132365341 @default.
- W4313236534 hasRelatedWork W1949477813 @default.
- W4313236534 hasRelatedWork W1983396513 @default.
- W4313236534 hasRelatedWork W2066200099 @default.
- W4313236534 hasRelatedWork W2070354370 @default.
- W4313236534 hasRelatedWork W2110084692 @default.
- W4313236534 hasRelatedWork W2158652075 @default.
- W4313236534 hasRelatedWork W2212952584 @default.
- W4313236534 hasRelatedWork W2349009129 @default.
- W4313236534 hasRelatedWork W2997763074 @default.
- W4313236534 hasRelatedWork W2903040050 @default.
- W4313236534 hasVolume "43" @default.
- W4313236534 isParatext "false" @default.
- W4313236534 isRetracted "false" @default.
- W4313236534 workType "article" @default.