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• W4313236635 abstract "To assess a novel intraoperative core biopsy technique to provide enhanced guidance in partial glossectomies.All patients diagnosed with squamous cell carcinoma of the oral tongue were eligible for study participation. Following anesthesia, the planned resection and three points midway between the gross tumor and the intended ablation were marked. A core biopsy was performed with a needle spring on each point and sent for frozen sections. The initially planned resection was executed if the cores returned free of tumor. In case of a positive core biopsy, a new 1-1.5 cm margin was marked around that point. The main outcome measure was the closest final margin diameter, especially the deep ones. Other outcome measures were the core biopsies' sensitivity, specificity, and negative predictive value. Complications were recorded.The final margins of 10 patients undergoing intraoperative core biopsies and 20 matched controls were analyzed. One patient had two positive cores and final negative margins after modifying the resection accordingly. Another patient had a positive biopsy diagnosed only on final pathology, and one close final margin. Patients that were operated with the new technique had larger margins compared to the controls: median (interquartile range) closest margin 5.95 (3.97; 9.63) mm versus 4 (2.25; 5) mm (p = 0.074) and median deep margin 8.6 (6.16; 10) mm versus 5 (3;10) mm (p = 0.411), respectively. There were no complications.A novel pre-resection intraoperative biopsy technique is presented. Core biopsies taken during glossectomies have the potential to prevent inadequate margins.3 Laryngoscope, 133:2232-2236, 2023." @default.
• W4313236635 created "2023-01-06" @default.
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• W4313236635 date "2022-12-28" @default.
• W4313236635 modified "2023-09-25" @default.
• W4313236635 title "Pre‐resection Intraoperative Core Biopsies in Oral Tongue Cancer—A Pilot Study" @default.
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• W4313236635 doi "https://doi.org/10.1002/lary.30546" @default.
• W4313236635 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36576073" @default.
• W4313236635 hasPublicationYear "2022" @default.
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