Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313236645> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4313236645 endingPage "401" @default.
- W4313236645 startingPage "395" @default.
- W4313236645 abstract "Compared to biological agents, little is known about the impact of sulfasalazine therapy on COVID-19 outcomes in patients with Axial Spondyloarthritis (AxSpA). Therefore, we aimed to evaluate the COVID-19 severity in AxSpAs receiving sulfasalazine and biologic-agent.A total of 219 SARS-CoV-2 positive AxSpA patients were retrospectively analyzed. COVID-19 pneumonia, hospitalization rate, and length of stay were used to determine COVID-19 severity. AxSpA patients were mainly grouped and compared as sulfasalazine and non-sulfasalazine. Afterward, we excluded no-treatment patients to reveal the drug's effects more clearly and regrouped AxSpA patients as sulfasalazine-monotherapy (34.3%), biologic-monotherapy (33.7%), and sulfasalazine + biologic (7.3%).Fifty-nine percent of the patients were male and the mean age was 45.0 years. Peripheral arthritis was 35% and uveitis 15%. In total, 41.5% of them have received sulfasalazine and 41.0% biologic agents, and the remaining patients with no AxSpA-specific treatment. In the first comparison, the sulfasalazine group had a higher age, more frequent COVID-19 pneumonia, hospitalization, and longer hospitalization than a non-sulfasalazine group. In the pairwise comparison of 3 treatment groups, the demographic and clinical features, the hospitalization rate and the length of hospital stay were similar but the sulfasalazine-monotherapy group had a higher frequency of COVID-19 pneumonia than the biologic-monotherapy group (23% vs. 7%, p = 0.008).Our results imply sulfasalazine may be related to more severe COVID-19 in AxSpA patients. These patients should be followed more carefully in the presence of COVID-19, regardless of reasons such as age, comorbidity, and extra-axial disease, and consideration of discontinuing sulfasalazine maybe even thought." @default.
- W4313236645 created "2023-01-06" @default.
- W4313236645 creator A5006334592 @default.
- W4313236645 creator A5014114164 @default.
- W4313236645 creator A5017596262 @default.
- W4313236645 creator A5024427640 @default.
- W4313236645 creator A5046019325 @default.
- W4313236645 creator A5048694869 @default.
- W4313236645 creator A5054295847 @default.
- W4313236645 creator A5059943791 @default.
- W4313236645 creator A5070815469 @default.
- W4313236645 creator A5072082690 @default.
- W4313236645 creator A5087693961 @default.
- W4313236645 creator A5090735825 @default.
- W4313236645 creator A5091764368 @default.
- W4313236645 date "2022-12-28" @default.
- W4313236645 modified "2023-09-27" @default.
- W4313236645 title "Effects of sulfasalazine in axial spondyloarthritis on COVID-19 outcomes: real-life data from a single center" @default.
- W4313236645 cites W1998196835 @default.
- W4313236645 cites W2137068168 @default.
- W4313236645 cites W2738144732 @default.
- W4313236645 cites W2783963160 @default.
- W4313236645 cites W2801222424 @default.
- W4313236645 cites W2972901075 @default.
- W4313236645 cites W3008028633 @default.
- W4313236645 cites W3008554056 @default.
- W4313236645 cites W3012310845 @default.
- W4313236645 cites W3015861468 @default.
- W4313236645 cites W3016830949 @default.
- W4313236645 cites W3017027582 @default.
- W4313236645 cites W3021463683 @default.
- W4313236645 cites W3024016727 @default.
- W4313236645 cites W3024177957 @default.
- W4313236645 cites W3094105410 @default.
- W4313236645 cites W3107355258 @default.
- W4313236645 cites W3112576601 @default.
- W4313236645 cites W3112902030 @default.
- W4313236645 cites W3116885809 @default.
- W4313236645 cites W3124810175 @default.
- W4313236645 cites W3138796149 @default.
- W4313236645 cites W3152961043 @default.
- W4313236645 cites W3154539840 @default.
- W4313236645 cites W3165656738 @default.
- W4313236645 cites W4235489476 @default.
- W4313236645 doi "https://doi.org/10.1080/08923973.2022.2160729" @default.
- W4313236645 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36537308" @default.
- W4313236645 hasPublicationYear "2022" @default.
- W4313236645 type Work @default.
- W4313236645 citedByCount "1" @default.
- W4313236645 countsByYear W43132366452023 @default.
- W4313236645 crossrefType "journal-article" @default.
- W4313236645 hasAuthorship W4313236645A5006334592 @default.
- W4313236645 hasAuthorship W4313236645A5014114164 @default.
- W4313236645 hasAuthorship W4313236645A5017596262 @default.
- W4313236645 hasAuthorship W4313236645A5024427640 @default.
- W4313236645 hasAuthorship W4313236645A5046019325 @default.
- W4313236645 hasAuthorship W4313236645A5048694869 @default.
- W4313236645 hasAuthorship W4313236645A5054295847 @default.
- W4313236645 hasAuthorship W4313236645A5059943791 @default.
- W4313236645 hasAuthorship W4313236645A5070815469 @default.
- W4313236645 hasAuthorship W4313236645A5072082690 @default.
- W4313236645 hasAuthorship W4313236645A5087693961 @default.
- W4313236645 hasAuthorship W4313236645A5090735825 @default.
- W4313236645 hasAuthorship W4313236645A5091764368 @default.
- W4313236645 hasConcept C126322002 @default.
- W4313236645 hasConcept C2777914695 @default.
- W4313236645 hasConcept C2779134260 @default.
- W4313236645 hasConcept C2779383735 @default.
- W4313236645 hasConcept C2780479503 @default.
- W4313236645 hasConcept C71924100 @default.
- W4313236645 hasConceptScore W4313236645C126322002 @default.
- W4313236645 hasConceptScore W4313236645C2777914695 @default.
- W4313236645 hasConceptScore W4313236645C2779134260 @default.
- W4313236645 hasConceptScore W4313236645C2779383735 @default.
- W4313236645 hasConceptScore W4313236645C2780479503 @default.
- W4313236645 hasConceptScore W4313236645C71924100 @default.
- W4313236645 hasIssue "4" @default.
- W4313236645 hasLocation W43132366451 @default.
- W4313236645 hasLocation W43132366452 @default.
- W4313236645 hasOpenAccess W4313236645 @default.
- W4313236645 hasPrimaryLocation W43132366451 @default.
- W4313236645 hasRelatedWork W1877883789 @default.
- W4313236645 hasRelatedWork W1995515455 @default.
- W4313236645 hasRelatedWork W2080531066 @default.
- W4313236645 hasRelatedWork W2316236384 @default.
- W4313236645 hasRelatedWork W2474749474 @default.
- W4313236645 hasRelatedWork W2748952813 @default.
- W4313236645 hasRelatedWork W2899084033 @default.
- W4313236645 hasRelatedWork W3031052312 @default.
- W4313236645 hasRelatedWork W3032375762 @default.
- W4313236645 hasRelatedWork W4253808419 @default.
- W4313236645 hasVolume "45" @default.
- W4313236645 isParatext "false" @default.
- W4313236645 isRetracted "false" @default.
- W4313236645 workType "article" @default.