FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313236880> ?p ?o ?g. }

• W4313236880 endingPage "75" @default.
• W4313236880 startingPage "61" @default.
• W4313236880 abstract "The amygdala is a complex brain structure in the vertebrate telencephalon, essential for regulating social behaviors, emotions, and (social) cognition. In contrast to the vast majority of neuron types described in the many nuclei of the mammalian amygdala, little is known about the neuronal diversity in non-mammals, making reconstruction of its evolution particularly difficult. Here, we characterize glutamatergic neuron types in the amygdala of the urodele amphibian Pleurodeles waltl. Our single-cell RNA sequencing data indicate the existence of at least ten distinct types and subtypes of glutamatergic neurons in the salamander amygdala. These neuron types are molecularly distinct from neurons in the ventral pallium (VP), suggesting that the pallial amygdala and the VP are two separate areas in the telencephalon. In situ hybridization for marker genes indicates that amygdalar glutamatergic neuron types are located in three major subdivisions: the lateral amygdala, the medial amygdala, and a newly defined area demarcated by high expression of the transcription factor Sim1. The gene expression profiles of these neuron types suggest similarities with specific neurons in the sauropsid and mammalian amygdala. In particular, we identify Sim1+ and Sim1+ Otp+ expressing neuron types, potentially homologous to the mammalian nucleus of the lateral olfactory tract (NLOT) and to hypothalamic-derived neurons of the medial amygdala, respectively. Taken together, our results reveal a surprising diversity of glutamatergic neuron types in the amygdala of salamanders, despite the anatomical simplicity of their brain. These results offer new insights on the cellular and anatomical complexity of the amygdala in tetrapod ancestors." @default.
• W4313236880 created "2023-01-06" @default.
• W4313236880 creator A5035402782 @default.
• W4313236880 creator A5061892411 @default.
• W4313236880 creator A5064053383 @default.
• W4313236880 creator A5084272195 @default.
• W4313236880 date "2022-12-27" @default.
• W4313236880 modified "2023-10-16" @default.
• W4313236880 title "Molecular Diversity of Neuron Types in the Salamander Amygdala and Implications for Amygdalar Evolution" @default.
• W4313236880 cites W1514288954 @default.
• W4313236880 cites W1564516432 @default.
• W4313236880 cites W1851837970 @default.
• W4313236880 cites W1930742286 @default.
• W4313236880 cites W1990500865 @default.
• W4313236880 cites W1998674408 @default.
• W4313236880 cites W1999077862 @default.
• W4313236880 cites W2003484830 @default.
• W4313236880 cites W2008106418 @default.
• W4313236880 cites W2011315139 @default.
• W4313236880 cites W2020561321 @default.
• W4313236880 cites W2020779715 @default.
• W4313236880 cites W2028474222 @default.
• W4313236880 cites W2032698939 @default.
• W4313236880 cites W2041888446 @default.
• W4313236880 cites W2044046576 @default.
• W4313236880 cites W2046784118 @default.
• W4313236880 cites W2049774100 @default.
• W4313236880 cites W2054921478 @default.
• W4313236880 cites W2056035374 @default.
• W4313236880 cites W2065777070 @default.
• W4313236880 cites W2077220958 @default.
• W4313236880 cites W2078320598 @default.
• W4313236880 cites W2080022252 @default.
• W4313236880 cites W2082376529 @default.
• W4313236880 cites W2086101496 @default.
• W4313236880 cites W2101098133 @default.
• W4313236880 cites W2126640721 @default.
• W4313236880 cites W2131845407 @default.
• W4313236880 cites W2144108721 @default.
• W4313236880 cites W2147302067 @default.
• W4313236880 cites W2162423225 @default.
• W4313236880 cites W2167279371 @default.
• W4313236880 cites W2170083890 @default.
• W4313236880 cites W2185927549 @default.
• W4313236880 cites W2463932398 @default.
• W4313236880 cites W2602577964 @default.
• W4313236880 cites W2619876151 @default.
• W4313236880 cites W2754763213 @default.
• W4313236880 cites W2762506555 @default.
• W4313236880 cites W2763143679 @default.
• W4313236880 cites W2777350706 @default.
• W4313236880 cites W2801175520 @default.
• W4313236880 cites W2897525775 @default.
• W4313236880 cites W2913755732 @default.
• W4313236880 cites W2949193645 @default.
• W4313236880 cites W2949693884 @default.
• W4313236880 cites W3006676863 @default.
• W4313236880 cites W3008663400 @default.
• W4313236880 cites W3023111531 @default.
• W4313236880 cites W3037442812 @default.
• W4313236880 cites W3041975023 @default.
• W4313236880 cites W3081575535 @default.
• W4313236880 cites W3114647779 @default.
• W4313236880 cites W3123417535 @default.
• W4313236880 cites W3123936995 @default.
• W4313236880 cites W3128953197 @default.
• W4313236880 cites W3152873294 @default.
• W4313236880 cites W3194086550 @default.
• W4313236880 cites W3204201357 @default.
• W4313236880 cites W3207558157 @default.
• W4313236880 cites W3214389270 @default.
• W4313236880 cites W4200183753 @default.
• W4313236880 cites W4200449643 @default.
• W4313236880 cites W4232573973 @default.
• W4313236880 cites W4252154660 @default.
• W4313236880 cites W4280520032 @default.
• W4313236880 cites W4294073634 @default.
• W4313236880 doi "https://doi.org/10.1159/000527899" @default.
• W4313236880 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36574764" @default.
• W4313236880 hasPublicationYear "2022" @default.
• W4313236880 type Work @default.
• W4313236880 citedByCount "0" @default.
• W4313236880 crossrefType "journal-article" @default.
• W4313236880 hasAuthorship W4313236880A5035402782 @default.
• W4313236880 hasAuthorship W4313236880A5061892411 @default.
• W4313236880 hasAuthorship W4313236880A5064053383 @default.
• W4313236880 hasAuthorship W4313236880A5084272195 @default.
• W4313236880 hasConcept C169760540 @default.
• W4313236880 hasConcept C170493617 @default.
• W4313236880 hasConcept C18903297 @default.
• W4313236880 hasConcept C2777948982 @default.
• W4313236880 hasConcept C2778794669 @default.
• W4313236880 hasConcept C2779144063 @default.
• W4313236880 hasConcept C2779999439 @default.
• W4313236880 hasConcept C2780648746 @default.
• W4313236880 hasConcept C2781465898 @default.
• W4313236880 hasConcept C529278444 @default.
• W4313236880 hasConcept C533869091 @default.

• next