Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313237434> ?p ?o ?g. }
- W4313237434 endingPage "1159" @default.
- W4313237434 startingPage "1146" @default.
- W4313237434 abstract "SUMMARY Marsdenia tenacissima is a medicinal plant widely distributed in the calcium‐rich karst regions of southwest China. However, the lack of a reference genome has hampered the implementation of molecular techniques in its breeding, pharmacology and domestication. We generated the chromosome‐level genome assembly in Apocynaceae using combined SMRT sequencing and Hi‐C. The genome length was 381.76 Mb, with 98.9% of it found on 11 chromosomes. The genome contained 222.63 Mb of repetitive sequences and 21 899 predicted gene models, with a contig N50 of 6.57 Mb. Phylogenetic analysis revealed that M. tenacissima diverged from Calotropis gigantea at least 13.43 million years ago. Comparative genomics showed that M. tenacissima underwent ancient shared whole‐genome duplication. This event, together with tandem duplication, contributed to 70.71% of gene‐family expansion. Both pseudogene analysis and selective pressure calculations suggested calcium‐related adaptive evolution in the M. tenacissima genome. Calcium‐induced differentially expressed genes (DEGs) were mainly enriched in cell‐wall‐related processes. Domains (e.g. Fasciclin and Amb_all) and cis ‐elements (e.g. MYB and MYC) frequently occurred in the coding and promoter regions of cell‐wall DEGs, respectively, and the expression levels of these genes correlated significantly with those of calcium‐signal‐related transcription factors. Moreover, calcium addition increased tenacissoside I, G and H contents. The availability of this high‐quality genome provides valuable genomic information for genetic breeding and molecular design, and lends insights into the calcium adaptation of M. tenacissima in karst areas ." @default.
- W4313237434 created "2023-01-06" @default.
- W4313237434 creator A5002483730 @default.
- W4313237434 creator A5002866142 @default.
- W4313237434 creator A5005589952 @default.
- W4313237434 creator A5006576057 @default.
- W4313237434 creator A5006645827 @default.
- W4313237434 creator A5010405193 @default.
- W4313237434 creator A5010533057 @default.
- W4313237434 creator A5015970180 @default.
- W4313237434 creator A5017306207 @default.
- W4313237434 creator A5023472197 @default.
- W4313237434 creator A5028047400 @default.
- W4313237434 creator A5031172993 @default.
- W4313237434 creator A5036820763 @default.
- W4313237434 creator A5036954040 @default.
- W4313237434 creator A5038517553 @default.
- W4313237434 creator A5045380175 @default.
- W4313237434 creator A5048233823 @default.
- W4313237434 creator A5074723444 @default.
- W4313237434 date "2023-02-16" @default.
- W4313237434 modified "2023-09-26" @default.
- W4313237434 title "<i>Marsdenia tenacissima</i> genome reveals calcium adaptation and tenacissoside biosynthesis" @default.
- W4313237434 cites W1183880170 @default.
- W4313237434 cites W1607531254 @default.
- W4313237434 cites W1900937478 @default.
- W4313237434 cites W1966051851 @default.
- W4313237434 cites W1966579843 @default.
- W4313237434 cites W1973062929 @default.
- W4313237434 cites W1977583449 @default.
- W4313237434 cites W1983238570 @default.
- W4313237434 cites W1983489372 @default.
- W4313237434 cites W1992356162 @default.
- W4313237434 cites W2009596137 @default.
- W4313237434 cites W2042228810 @default.
- W4313237434 cites W2043669850 @default.
- W4313237434 cites W2057844822 @default.
- W4313237434 cites W2073074612 @default.
- W4313237434 cites W2095799613 @default.
- W4313237434 cites W2097160089 @default.
- W4313237434 cites W2103441770 @default.
- W4313237434 cites W2104005232 @default.
- W4313237434 cites W2108787198 @default.
- W4313237434 cites W2110335151 @default.
- W4313237434 cites W2112208205 @default.
- W4313237434 cites W2118628922 @default.
- W4313237434 cites W2118970626 @default.
- W4313237434 cites W2120217572 @default.
- W4313237434 cites W2121167940 @default.
- W4313237434 cites W2138098955 @default.
- W4313237434 cites W2138354840 @default.
- W4313237434 cites W2138884756 @default.
- W4313237434 cites W2140444329 @default.
- W4313237434 cites W2158804744 @default.
- W4313237434 cites W2159038577 @default.
- W4313237434 cites W2167730133 @default.
- W4313237434 cites W2179438025 @default.
- W4313237434 cites W2188177493 @default.
- W4313237434 cites W2575750030 @default.
- W4313237434 cites W2604308930 @default.
- W4313237434 cites W2609014879 @default.
- W4313237434 cites W2743699200 @default.
- W4313237434 cites W2765334989 @default.
- W4313237434 cites W2770129280 @default.
- W4313237434 cites W2772933620 @default.
- W4313237434 cites W2786706225 @default.
- W4313237434 cites W2789764809 @default.
- W4313237434 cites W2800141836 @default.
- W4313237434 cites W2888202666 @default.
- W4313237434 cites W2907966016 @default.
- W4313237434 cites W2912156549 @default.
- W4313237434 cites W2945924357 @default.
- W4313237434 cites W2949086752 @default.
- W4313237434 cites W2950354111 @default.
- W4313237434 cites W2954962060 @default.
- W4313237434 cites W2964849163 @default.
- W4313237434 cites W2969927170 @default.
- W4313237434 cites W2996650952 @default.
- W4313237434 cites W2998447965 @default.
- W4313237434 cites W3004361233 @default.
- W4313237434 cites W3010932628 @default.
- W4313237434 cites W3047995510 @default.
- W4313237434 cites W3164271582 @default.
- W4313237434 cites W3216482396 @default.
- W4313237434 cites W4211253200 @default.
- W4313237434 doi "https://doi.org/10.1111/tpj.16081" @default.
- W4313237434 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36575579" @default.
- W4313237434 hasPublicationYear "2023" @default.
- W4313237434 type Work @default.
- W4313237434 citedByCount "2" @default.
- W4313237434 countsByYear W43132374342023 @default.
- W4313237434 crossrefType "journal-article" @default.
- W4313237434 hasAuthorship W4313237434A5002483730 @default.
- W4313237434 hasAuthorship W4313237434A5002866142 @default.
- W4313237434 hasAuthorship W4313237434A5005589952 @default.
- W4313237434 hasAuthorship W4313237434A5006576057 @default.
- W4313237434 hasAuthorship W4313237434A5006645827 @default.
- W4313237434 hasAuthorship W4313237434A5010405193 @default.