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• W4313237442 startingPage "977" @default.
• W4313237442 abstract "Abstract Since the brain was found to be somehow flexible, plastic, researchers worldwide have been trying to comprehend its fundamentals to better understand the brain itself, make predictions, disentangle the neurobiology of brain diseases, and finally propose up-to-date treatments. Neuroplasticity is simple as a concept, but extremely complex when it comes to its mechanisms. This review aims to bring to light an aspect about neuroplasticity that is often not given enough attention as it should, the fact that the brain’s ability to change would include its ability to disconnect synapses. So, neuronal shrinkage, decrease in spine density or dendritic complexity should be included within the concept of neuroplasticity as part of its mechanisms, not as an impairment of it. To that end, we extensively describe a variety of studies involving topics such as neurodevelopment, aging, stress, memory and homeostatic plasticity to highlight how the weakening and disconnection of synapses organically permeate the brain in so many ways as a good practice of its intrinsic physiology. Therefore, we propose to break down neuroplasticity into two sub-concepts, “upward neuroplasticity” for changes related to synaptic construction and “downward neuroplasticity” for changes related to synaptic deconstruction. With these sub-concepts, neuroplasticity could be better understood from a bigger landscape as a vector in which both directions could be taken for the brain to flexibly adapt to certain demands. Such a paradigm shift would allow a better understanding of the concept of neuroplasticity to avoid any data interpretation bias, once it makes clear that there is no morality with regard to the organic and physiological changes that involve dynamic biological systems as seen in the brain." @default.
• W4313237442 created "2023-01-06" @default.
• W4313237442 creator A5008749192 @default.
• W4313237442 creator A5073593635 @default.
• W4313237442 date "2022-12-27" @default.
• W4313237442 modified "2023-10-14" @default.
• W4313237442 title "The times they are a-changin’: a proposal on how brain flexibility goes beyond the obvious to include the concepts of “upward” and “downward” to neuroplasticity" @default.
• W4313237442 cites W1489333352 @default.
• W4313237442 cites W1539532151 @default.
• W4313237442 cites W1553814286 @default.
• W4313237442 cites W1555506001 @default.
• W4313237442 cites W1557933310 @default.
• W4313237442 cites W1576581762 @default.
• W4313237442 cites W1593904343 @default.
• W4313237442 cites W1596533183 @default.
• W4313237442 cites W1597519089 @default.
• W4313237442 cites W1626176125 @default.
• W4313237442 cites W1733248925 @default.
• W4313237442 cites W1745608382 @default.
• W4313237442 cites W1757333299 @default.
• W4313237442 cites W1804267428 @default.
• W4313237442 cites W1912895564 @default.
• W4313237442 cites W1955317537 @default.
• W4313237442 cites W1964570010 @default.
• W4313237442 cites W1965960354 @default.
• W4313237442 cites W1966157184 @default.
• W4313237442 cites W1966805834 @default.
• W4313237442 cites W1967305188 @default.
• W4313237442 cites W1967534538 @default.
• W4313237442 cites W1968763273 @default.
• W4313237442 cites W1969781703 @default.
• W4313237442 cites W1969845534 @default.
• W4313237442 cites W1970685218 @default.
• W4313237442 cites W1971063595 @default.
• W4313237442 cites W1973311433 @default.
• W4313237442 cites W1975002939 @default.
• W4313237442 cites W1975055665 @default.
• W4313237442 cites W1975368375 @default.
• W4313237442 cites W1978226315 @default.
• W4313237442 cites W1978408307 @default.
• W4313237442 cites W1978733078 @default.
• W4313237442 cites W1978926494 @default.
• W4313237442 cites W1979956591 @default.
• W4313237442 cites W1980452424 @default.
• W4313237442 cites W1980576528 @default.
• W4313237442 cites W1981114447 @default.
• W4313237442 cites W1981957263 @default.
• W4313237442 cites W1982270009 @default.
• W4313237442 cites W1982280357 @default.
• W4313237442 cites W1982643425 @default.
• W4313237442 cites W1983617759 @default.
• W4313237442 cites W1983916806 @default.
• W4313237442 cites W1985168009 @default.
• W4313237442 cites W1985322212 @default.
• W4313237442 cites W1986246328 @default.
• W4313237442 cites W1986552075 @default.
• W4313237442 cites W1987683287 @default.
• W4313237442 cites W1988059569 @default.
• W4313237442 cites W1990294595 @default.
• W4313237442 cites W1993475351 @default.
• W4313237442 cites W1994253126 @default.
• W4313237442 cites W1995322135 @default.
• W4313237442 cites W1995698894 @default.
• W4313237442 cites W1996838710 @default.
• W4313237442 cites W1999321510 @default.
• W4313237442 cites W1999653836 @default.
• W4313237442 cites W2000282078 @default.
• W4313237442 cites W2000520243 @default.
• W4313237442 cites W2001565222 @default.
• W4313237442 cites W2006492271 @default.
• W4313237442 cites W2007532471 @default.
• W4313237442 cites W2009000833 @default.
• W4313237442 cites W2011046807 @default.
• W4313237442 cites W2011580597 @default.
• W4313237442 cites W2014840758 @default.
• W4313237442 cites W2015464362 @default.
• W4313237442 cites W2015574237 @default.
• W4313237442 cites W2015701831 @default.
• W4313237442 cites W2020112095 @default.
• W4313237442 cites W2021158045 @default.
• W4313237442 cites W2021246719 @default.
• W4313237442 cites W2021637918 @default.
• W4313237442 cites W2022424636 @default.
• W4313237442 cites W2023465483 @default.
• W4313237442 cites W2024583667 @default.
• W4313237442 cites W2024614800 @default.
• W4313237442 cites W2026022097 @default.
• W4313237442 cites W2027109102 @default.
• W4313237442 cites W2028923096 @default.
• W4313237442 cites W2029406839 @default.
• W4313237442 cites W2030868131 @default.
• W4313237442 cites W2031313254 @default.
• W4313237442 cites W2032476754 @default.
• W4313237442 cites W2033842034 @default.
• W4313237442 cites W2035319691 @default.
• W4313237442 cites W2036029991 @default.
• W4313237442 cites W2036284062 @default.
• W4313237442 cites W2036491149 @default.

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