Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313237470> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W4313237470 endingPage "886" @default.
- W4313237470 startingPage "877" @default.
- W4313237470 abstract "Surgical resection of posterior fossa tumors (PFT) in the pediatric age group often results in significant intraoperative blood loss. The primary objective was to assess the effect of tranexamic acid (TXA) on blood loss and transfusion requirement in pediatric patients undergoing excision of PFT.In this retrospective study, all pediatric patients ≤ 18 years, who underwent PFT resection over a period of 7 years, were included. The patient and surgical characteristics, estimated blood loss (EBL), the need for blood and blood product transfusion, use of crystalloids, vasopressors, and any adverse events like seizures and thromboembolic events were recorded and compared between Group A who received TXA and Group B who did not.The study included 50 patients, out of which 36 belonged to Group A and 14 to Group B. The median age was 8 years (IQR, 2-17) and the mean BMI was 16.46 ± 4.11 kg/m2. The mean EBL was 224.29 ± 110.36 ml in group A (n = 36) and 362 ± 180.11 ml in group B (n = 14) (p = 0.007). The intraoperative volume of crystalloid use was significantly higher in group B (p = 0.04). The requirement of blood and blood product transfusion was similar between the groups, but the volume of blood transfusion per kg body weight was higher in group B, 8.3 (IQR, 6.7-11.1) ml/kg in Group A versus 10.5 (IQR, 8.1-16.1) ml/kg in Group B (p-value 0.3). The rates of complications noted in the form of seizures and thromboembolic events were comparable.The use of TXA in the pediatric population undergoing PFT resection aids in reducing blood loss during the surgery without increasing complications." @default.
- W4313237470 created "2023-01-06" @default.
- W4313237470 creator A5005760028 @default.
- W4313237470 creator A5022670264 @default.
- W4313237470 creator A5041015782 @default.
- W4313237470 creator A5047375309 @default.
- W4313237470 creator A5060848372 @default.
- W4313237470 date "2022-12-28" @default.
- W4313237470 modified "2023-10-02" @default.
- W4313237470 title "Effect of administration of tranexamic acid on blood loss and transfusion requirements in children undergoing posterior fossa tumor excision: a retrospective cohort study" @default.
- W4313237470 cites W1483535956 @default.
- W4313237470 cites W1972037865 @default.
- W4313237470 cites W1973359638 @default.
- W4313237470 cites W1978799382 @default.
- W4313237470 cites W2011749594 @default.
- W4313237470 cites W2016016217 @default.
- W4313237470 cites W2040900203 @default.
- W4313237470 cites W2050962336 @default.
- W4313237470 cites W2055116941 @default.
- W4313237470 cites W2075039980 @default.
- W4313237470 cites W2091922186 @default.
- W4313237470 cites W2093467941 @default.
- W4313237470 cites W2299129461 @default.
- W4313237470 cites W2317198275 @default.
- W4313237470 cites W2334165530 @default.
- W4313237470 cites W2334692376 @default.
- W4313237470 cites W2346498785 @default.
- W4313237470 cites W2594703682 @default.
- W4313237470 cites W2611394318 @default.
- W4313237470 cites W2769916425 @default.
- W4313237470 cites W2770171611 @default.
- W4313237470 cites W2792487481 @default.
- W4313237470 cites W2966325987 @default.
- W4313237470 cites W3036556465 @default.
- W4313237470 cites W3038652724 @default.
- W4313237470 cites W4200310865 @default.
- W4313237470 doi "https://doi.org/10.1007/s00381-022-05758-3" @default.
- W4313237470 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36576551" @default.
- W4313237470 hasPublicationYear "2022" @default.
- W4313237470 type Work @default.
- W4313237470 citedByCount "0" @default.
- W4313237470 crossrefType "journal-article" @default.
- W4313237470 hasAuthorship W4313237470A5005760028 @default.
- W4313237470 hasAuthorship W4313237470A5022670264 @default.
- W4313237470 hasAuthorship W4313237470A5041015782 @default.
- W4313237470 hasAuthorship W4313237470A5047375309 @default.
- W4313237470 hasAuthorship W4313237470A5060848372 @default.
- W4313237470 hasBestOaLocation W43132374702 @default.
- W4313237470 hasConcept C126322002 @default.
- W4313237470 hasConcept C12770488 @default.
- W4313237470 hasConcept C141071460 @default.
- W4313237470 hasConcept C167135981 @default.
- W4313237470 hasConcept C197934379 @default.
- W4313237470 hasConcept C2777396833 @default.
- W4313237470 hasConcept C2777785397 @default.
- W4313237470 hasConcept C2779637338 @default.
- W4313237470 hasConcept C2780014101 @default.
- W4313237470 hasConcept C2991743468 @default.
- W4313237470 hasConcept C37557685 @default.
- W4313237470 hasConcept C42219234 @default.
- W4313237470 hasConcept C71924100 @default.
- W4313237470 hasConceptScore W4313237470C126322002 @default.
- W4313237470 hasConceptScore W4313237470C12770488 @default.
- W4313237470 hasConceptScore W4313237470C141071460 @default.
- W4313237470 hasConceptScore W4313237470C167135981 @default.
- W4313237470 hasConceptScore W4313237470C197934379 @default.
- W4313237470 hasConceptScore W4313237470C2777396833 @default.
- W4313237470 hasConceptScore W4313237470C2777785397 @default.
- W4313237470 hasConceptScore W4313237470C2779637338 @default.
- W4313237470 hasConceptScore W4313237470C2780014101 @default.
- W4313237470 hasConceptScore W4313237470C2991743468 @default.
- W4313237470 hasConceptScore W4313237470C37557685 @default.
- W4313237470 hasConceptScore W4313237470C42219234 @default.
- W4313237470 hasConceptScore W4313237470C71924100 @default.
- W4313237470 hasIssue "4" @default.
- W4313237470 hasLocation W43132374701 @default.
- W4313237470 hasLocation W43132374702 @default.
- W4313237470 hasLocation W43132374703 @default.
- W4313237470 hasOpenAccess W4313237470 @default.
- W4313237470 hasPrimaryLocation W43132374701 @default.
- W4313237470 hasRelatedWork W1999291976 @default.
- W4313237470 hasRelatedWork W2317612395 @default.
- W4313237470 hasRelatedWork W2328659429 @default.
- W4313237470 hasRelatedWork W2332193474 @default.
- W4313237470 hasRelatedWork W2800022962 @default.
- W4313237470 hasRelatedWork W2883682937 @default.
- W4313237470 hasRelatedWork W3009399736 @default.
- W4313237470 hasRelatedWork W3136648826 @default.
- W4313237470 hasRelatedWork W4226535647 @default.
- W4313237470 hasRelatedWork W4233116497 @default.
- W4313237470 hasVolume "39" @default.
- W4313237470 isParatext "false" @default.
- W4313237470 isRetracted "false" @default.
- W4313237470 workType "article" @default.