Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313237727> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W4313237727 endingPage "15" @default.
- W4313237727 startingPage "11" @default.
- W4313237727 abstract "Abstract The fragility index (FI) is a sensitivity analysis of the statistically significant result of a clinical study. It is the number of hypothetical changes in the primary event of one of the two cohorts in a 1‐to‐1 comparative trial to render the statistically significant result non‐significant (ie, to alter the P ‐value from ≤0.05 to >0.05). The FI can be compared with the patient drop‐out rates and protocol violations, which, if much higher than the FI, may arguably suggest less robustness/stability of the trial's results. To illustrate the concept, we have chosen the Term Breech Trial (TBT) as a case study. The TBT results favor planned cesarean birth, as opposed to planned vaginal delivery, in the term singleton fetus with breech presentation. Our analysis shows that the FI of the TBT is 21, which is small in comparison to the number (hundreds) of protocol violations present. Some experts have suggested the inclusion of the FI in data analysis and subsequent discussion of clinical trial data. Routine use of such a metric may be valuable in encouraging readers to maintain a healthy degree of skepticism, especially when interpreting trial results which may directly influence clinical practice." @default.
- W4313237727 created "2023-01-06" @default.
- W4313237727 creator A5050548542 @default.
- W4313237727 creator A5071067449 @default.
- W4313237727 creator A5079659880 @default.
- W4313237727 creator A5084545234 @default.
- W4313237727 date "2022-12-28" @default.
- W4313237727 modified "2023-10-03" @default.
- W4313237727 title "Introducing the fragility index—A case study using the Term Breech Trial" @default.
- W4313237727 cites W1877645643 @default.
- W4313237727 cites W1987641558 @default.
- W4313237727 cites W1997369007 @default.
- W4313237727 cites W2016828082 @default.
- W4313237727 cites W2040827170 @default.
- W4313237727 cites W2059348534 @default.
- W4313237727 cites W2081814119 @default.
- W4313237727 cites W2140332437 @default.
- W4313237727 cites W2145443732 @default.
- W4313237727 cites W2164957370 @default.
- W4313237727 cites W2167129734 @default.
- W4313237727 cites W2211143780 @default.
- W4313237727 cites W2404732677 @default.
- W4313237727 cites W2467274687 @default.
- W4313237727 cites W2563466275 @default.
- W4313237727 cites W2925120686 @default.
- W4313237727 cites W3022046680 @default.
- W4313237727 cites W3191954333 @default.
- W4313237727 cites W4248078194 @default.
- W4313237727 cites W4251170725 @default.
- W4313237727 cites W4361868435 @default.
- W4313237727 doi "https://doi.org/10.1111/birt.12698" @default.
- W4313237727 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36576726" @default.
- W4313237727 hasPublicationYear "2022" @default.
- W4313237727 type Work @default.
- W4313237727 citedByCount "0" @default.
- W4313237727 crossrefType "journal-article" @default.
- W4313237727 hasAuthorship W4313237727A5050548542 @default.
- W4313237727 hasAuthorship W4313237727A5071067449 @default.
- W4313237727 hasAuthorship W4313237727A5079659880 @default.
- W4313237727 hasAuthorship W4313237727A5084545234 @default.
- W4313237727 hasBestOaLocation W43132377271 @default.
- W4313237727 hasConcept C117354338 @default.
- W4313237727 hasConcept C121332964 @default.
- W4313237727 hasConcept C126322002 @default.
- W4313237727 hasConcept C147789679 @default.
- W4313237727 hasConcept C185592680 @default.
- W4313237727 hasConcept C187212893 @default.
- W4313237727 hasConcept C2779234561 @default.
- W4313237727 hasConcept C3018664633 @default.
- W4313237727 hasConcept C535046627 @default.
- W4313237727 hasConcept C54355233 @default.
- W4313237727 hasConcept C61797465 @default.
- W4313237727 hasConcept C62520636 @default.
- W4313237727 hasConcept C71924100 @default.
- W4313237727 hasConcept C80191262 @default.
- W4313237727 hasConcept C86803240 @default.
- W4313237727 hasConceptScore W4313237727C117354338 @default.
- W4313237727 hasConceptScore W4313237727C121332964 @default.
- W4313237727 hasConceptScore W4313237727C126322002 @default.
- W4313237727 hasConceptScore W4313237727C147789679 @default.
- W4313237727 hasConceptScore W4313237727C185592680 @default.
- W4313237727 hasConceptScore W4313237727C187212893 @default.
- W4313237727 hasConceptScore W4313237727C2779234561 @default.
- W4313237727 hasConceptScore W4313237727C3018664633 @default.
- W4313237727 hasConceptScore W4313237727C535046627 @default.
- W4313237727 hasConceptScore W4313237727C54355233 @default.
- W4313237727 hasConceptScore W4313237727C61797465 @default.
- W4313237727 hasConceptScore W4313237727C62520636 @default.
- W4313237727 hasConceptScore W4313237727C71924100 @default.
- W4313237727 hasConceptScore W4313237727C80191262 @default.
- W4313237727 hasConceptScore W4313237727C86803240 @default.
- W4313237727 hasIssue "1" @default.
- W4313237727 hasLocation W43132377271 @default.
- W4313237727 hasLocation W43132377272 @default.
- W4313237727 hasOpenAccess W4313237727 @default.
- W4313237727 hasPrimaryLocation W43132377271 @default.
- W4313237727 hasRelatedWork W1593492907 @default.
- W4313237727 hasRelatedWork W2077097207 @default.
- W4313237727 hasRelatedWork W2167782902 @default.
- W4313237727 hasRelatedWork W2465137891 @default.
- W4313237727 hasRelatedWork W2618474469 @default.
- W4313237727 hasRelatedWork W2737302819 @default.
- W4313237727 hasRelatedWork W2977839445 @default.
- W4313237727 hasRelatedWork W4233017164 @default.
- W4313237727 hasRelatedWork W4246737094 @default.
- W4313237727 hasRelatedWork W2162722869 @default.
- W4313237727 hasVolume "50" @default.
- W4313237727 isParatext "false" @default.
- W4313237727 isRetracted "false" @default.
- W4313237727 workType "article" @default.