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- W4313237907 abstract "Abstract To investigate the association between enteric pathogens, fecal microbes, and child growth, we conducted a prospective cohort study of 236 children <5 years of age in rural eastern Democratic Republic of the Congo. We analyzed baseline fecal specimens by quantitative PCR and measured child height and weight at baseline and growth at a 6-month follow-up. At baseline, 66% (156/236) of children had >3 pathogens in their feces. We observed larger increases in height-for-age-z-scores from baseline to the 6-month follow-up among children with Akkermansia muciniphila in their feces (coefficient 0.02 [95% CI 0.0001–0.04]; p = 0.04). Children with Cryptosporidium in their feces had larger declines in weight-for-height/length z-scores from baseline to the 6-month follow-up (coefficient –0.03 [95% CI –0.05 to –0.005]; p = 0.02). Our study showed high prevalence of enteric pathogens among this pediatric cohort and suggests A. muciniphila can potentially serve as a probiotic to improve child growth." @default.
- W4313237907 created "2023-01-06" @default.
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- W4313237907 date "2023-01-01" @default.
- W4313237907 modified "2023-10-18" @default.
- W4313237907 title "<i>Akkermansia muciniphila</i> Associated with Improved Linear Growth among Young Children, Democratic Republic of the Congo" @default.
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- W4313237907 doi "https://doi.org/10.3201/eid2901.212118" @default.
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