FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313238087> ?p ?o ?g. }

• W4313238087 endingPage "556" @default.
• W4313238087 startingPage "556" @default.
• W4313238087 abstract "Ion transport molecules are involved in many physiological and pathological processes and are considered potential targets for cancer treatment. In the large family of ion transport molecules, potassium (K) ion channels, as surface-expressed proteins, show the highest variability and most frequent expression changes in many tumor types. The key to exploring the permeation of K+ through potassium channels lies in the conserved sequence TVGYG, which is common in the selectivity filter (SF) region of all potassium channels. We found that the K+ flux significantly increased with the help of a specific frequency terahertz electromagnetic wave (51.87 THz) in the KcsA channel using a molecular dynamics combined model through the combined simulation of the constant electric field method and ion imbalance method. This frequency has the strongest absorption peak in the infrared spectrum of -C=O groups in the SF region. With the applied electric field of 51.87 THz, the Y78 residue at the S1 site of the SF has a smaller vibration amplitude and a more stable structure, which enables the K+ to bind closely with the carbonyl oxygen atoms in the SF and realize ion conduction in a more efficient direct Coulomb knock-on." @default.
• W4313238087 created "2023-01-06" @default.
• W4313238087 creator A5004967576 @default.
• W4313238087 creator A5014965312 @default.
• W4313238087 creator A5039360448 @default.
• W4313238087 creator A5078234546 @default.
• W4313238087 creator A5078545994 @default.
• W4313238087 creator A5084251242 @default.
• W4313238087 date "2022-12-29" @default.
• W4313238087 modified "2023-10-14" @default.
• W4313238087 title "Regulation of Ion Permeation of the KcsA Channel by Applied Midinfrared Field" @default.
• W4313238087 cites W1834003507 @default.
• W4313238087 cites W1966078827 @default.
• W4313238087 cites W1968695132 @default.
• W4313238087 cites W1972800394 @default.
• W4313238087 cites W1991033228 @default.
• W4313238087 cites W1994286014 @default.
• W4313238087 cites W2000431734 @default.
• W4313238087 cites W2007313234 @default.
• W4313238087 cites W2015233467 @default.
• W4313238087 cites W2021520922 @default.
• W4313238087 cites W2026475386 @default.
• W4313238087 cites W2026877196 @default.
• W4313238087 cites W2032855201 @default.
• W4313238087 cites W2036260386 @default.
• W4313238087 cites W2037539407 @default.
• W4313238087 cites W2062803251 @default.
• W4313238087 cites W2065570378 @default.
• W4313238087 cites W2069420032 @default.
• W4313238087 cites W2082307134 @default.
• W4313238087 cites W2086977354 @default.
• W4313238087 cites W2089345692 @default.
• W4313238087 cites W2089400376 @default.
• W4313238087 cites W2095134060 @default.
• W4313238087 cites W2109258309 @default.
• W4313238087 cites W2111138318 @default.
• W4313238087 cites W2113789703 @default.
• W4313238087 cites W2122042576 @default.
• W4313238087 cites W2122590911 @default.
• W4313238087 cites W2124653618 @default.
• W4313238087 cites W2132262459 @default.
• W4313238087 cites W2143070723 @default.
• W4313238087 cites W2147885377 @default.
• W4313238087 cites W2150323741 @default.
• W4313238087 cites W2274231905 @default.
• W4313238087 cites W2303352597 @default.
• W4313238087 cites W2486696844 @default.
• W4313238087 cites W2515009802 @default.
• W4313238087 cites W2735199155 @default.
• W4313238087 cites W2769677126 @default.
• W4313238087 cites W2785885120 @default.
• W4313238087 cites W2883325391 @default.
• W4313238087 cites W2970292016 @default.
• W4313238087 cites W2971464705 @default.
• W4313238087 cites W3036892051 @default.
• W4313238087 cites W3041698669 @default.
• W4313238087 cites W3131573550 @default.
• W4313238087 cites W3135220202 @default.
• W4313238087 cites W3173775082 @default.
• W4313238087 cites W4210362665 @default.
• W4313238087 doi "https://doi.org/10.3390/ijms24010556" @default.
• W4313238087 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36613998" @default.
• W4313238087 hasPublicationYear "2022" @default.
• W4313238087 type Work @default.
• W4313238087 citedByCount "1" @default.
• W4313238087 countsByYear W43132380872023 @default.
• W4313238087 crossrefType "journal-article" @default.
• W4313238087 hasAuthorship W4313238087A5004967576 @default.
• W4313238087 hasAuthorship W4313238087A5014965312 @default.
• W4313238087 hasAuthorship W4313238087A5039360448 @default.
• W4313238087 hasAuthorship W4313238087A5078234546 @default.
• W4313238087 hasAuthorship W4313238087A5078545994 @default.
• W4313238087 hasAuthorship W4313238087A5084251242 @default.
• W4313238087 hasBestOaLocation W43132380871 @default.
• W4313238087 hasConcept C113196181 @default.
• W4313238087 hasConcept C121332964 @default.
• W4313238087 hasConcept C12554922 @default.
• W4313238087 hasConcept C145148216 @default.
• W4313238087 hasConcept C147597530 @default.
• W4313238087 hasConcept C159467904 @default.
• W4313238087 hasConcept C170493617 @default.
• W4313238087 hasConcept C178790620 @default.
• W4313238087 hasConcept C184779094 @default.
• W4313238087 hasConcept C185592680 @default.
• W4313238087 hasConcept C32909587 @default.
• W4313238087 hasConcept C41625074 @default.
• W4313238087 hasConcept C41999313 @default.
• W4313238087 hasConcept C43617362 @default.
• W4313238087 hasConcept C45516822 @default.
• W4313238087 hasConcept C50254741 @default.
• W4313238087 hasConcept C50670333 @default.
• W4313238087 hasConcept C55493867 @default.
• W4313238087 hasConcept C59593255 @default.
• W4313238087 hasConcept C60799052 @default.
• W4313238087 hasConcept C62520636 @default.
• W4313238087 hasConcept C83743174 @default.
• W4313238087 hasConcept C86803240 @default.
• W4313238087 hasConceptScore W4313238087C113196181 @default.

• next