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- W4313238097 endingPage "537" @default.
- W4313238097 startingPage "537" @default.
- W4313238097 abstract "Primary liver cancer is a heterogeneous disease. Liver cancer metabolism includes both the reprogramming of intracellular metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor microenvironment and fluctuations in regular tissue metabolism. Currently, metabolomics and metabolite profiling in liver cirrhosis, liver cancer, and hepatocellular carcinoma (HCC) have been in the spotlight in terms of cancer diagnosis, monitoring, and therapy. Metabolomics is the global analysis of small molecules, chemicals, and metabolites. Metabolomics technologies can provide critical information about the liver cancer state. Here, we review how liver cirrhosis, liver cancer, and HCC therapies interact with metabolism at the cellular and systemic levels. An overview of liver metabolomics is provided, with a focus on currently available technologies and how they have been used in clinical and translational research. We also list scalable methods, including chemometrics, followed by pathway processing in liver cancer. We conclude that important drivers of metabolomics science and scientific technologies are novel therapeutic tools and liver cancer biomarker analysis." @default.
- W4313238097 created "2023-01-06" @default.
- W4313238097 creator A5006854066 @default.
- W4313238097 creator A5029173848 @default.
- W4313238097 creator A5088778314 @default.
- W4313238097 date "2022-12-28" @default.
- W4313238097 modified "2023-10-09" @default.
- W4313238097 title "Microbiome and Metabolomics in Liver Cancer: Scientific Technology" @default.
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