Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313238720> ?p ?o ?g. }
- W4313238720 endingPage "46" @default.
- W4313238720 startingPage "46" @default.
- W4313238720 abstract "Natural products are an important source of drug lead compounds, and natural products with significant biological activity are constantly being discovered and used in clinical practice. At present, natural products play an important role in the targeted therapy of cancer, cardiovascular and cerebrovascular diseases, nervous system diseases, and autoimmune diseases. Meanwhile, in recent years, the rise of protein-targeted degradation technologies, such as proteolysis-targeting chimeras (PROTACs) and molecular glues, has provided a new solution for drug resistance caused by clinical molecular-targeting drugs. It is noteworthy that natural products and their derivatives, as important components of PROTACs and molecular glues, play an important role in the development of protein-targeting drugs. Hence, this review summarized the protein-targeted degradation agents based on natural products, such as PROTACs and molecular glues. More natural products with the potential to be used in the development of PROTACs and molecular glues as targeted protein degradation agents are still being investigated." @default.
- W4313238720 created "2023-01-06" @default.
- W4313238720 creator A5038805449 @default.
- W4313238720 creator A5048473316 @default.
- W4313238720 creator A5056723526 @default.
- W4313238720 creator A5069101058 @default.
- W4313238720 creator A5081158417 @default.
- W4313238720 date "2022-12-28" @default.
- W4313238720 modified "2023-10-14" @default.
- W4313238720 title "Protein-Targeted Degradation Agents Based on Natural Products" @default.
- W4313238720 cites W1972633502 @default.
- W4313238720 cites W1976946414 @default.
- W4313238720 cites W2000589669 @default.
- W4313238720 cites W2016908879 @default.
- W4313238720 cites W2022394817 @default.
- W4313238720 cites W2025031463 @default.
- W4313238720 cites W2027444723 @default.
- W4313238720 cites W2031201349 @default.
- W4313238720 cites W2031982459 @default.
- W4313238720 cites W2039944972 @default.
- W4313238720 cites W2048392782 @default.
- W4313238720 cites W2050244937 @default.
- W4313238720 cites W2052268618 @default.
- W4313238720 cites W2066584196 @default.
- W4313238720 cites W2072300064 @default.
- W4313238720 cites W2079605252 @default.
- W4313238720 cites W2082633436 @default.
- W4313238720 cites W2104794408 @default.
- W4313238720 cites W2131441324 @default.
- W4313238720 cites W2141474275 @default.
- W4313238720 cites W2146064872 @default.
- W4313238720 cites W2151683271 @default.
- W4313238720 cites W2155589321 @default.
- W4313238720 cites W2160648204 @default.
- W4313238720 cites W2163158822 @default.
- W4313238720 cites W2232768243 @default.
- W4313238720 cites W2735605417 @default.
- W4313238720 cites W2757693305 @default.
- W4313238720 cites W2778368398 @default.
- W4313238720 cites W2837034380 @default.
- W4313238720 cites W2888785247 @default.
- W4313238720 cites W2898621430 @default.
- W4313238720 cites W2902144856 @default.
- W4313238720 cites W2904458560 @default.
- W4313238720 cites W2905732834 @default.
- W4313238720 cites W2949236218 @default.
- W4313238720 cites W2956604676 @default.
- W4313238720 cites W2969441343 @default.
- W4313238720 cites W2976352578 @default.
- W4313238720 cites W2977584853 @default.
- W4313238720 cites W2992546470 @default.
- W4313238720 cites W3007276561 @default.
- W4313238720 cites W3009586897 @default.
- W4313238720 cites W3012278138 @default.
- W4313238720 cites W3017996554 @default.
- W4313238720 cites W3021599444 @default.
- W4313238720 cites W3034021518 @default.
- W4313238720 cites W3036135201 @default.
- W4313238720 cites W3036563774 @default.
- W4313238720 cites W3045619116 @default.
- W4313238720 cites W3046518781 @default.
- W4313238720 cites W3049656208 @default.
- W4313238720 cites W3049724121 @default.
- W4313238720 cites W3084826602 @default.
- W4313238720 cites W3092090741 @default.
- W4313238720 cites W3095673375 @default.
- W4313238720 cites W3119787068 @default.
- W4313238720 cites W3134757317 @default.
- W4313238720 cites W3140378160 @default.
- W4313238720 cites W3156299359 @default.
- W4313238720 cites W3163700030 @default.
- W4313238720 cites W3165173500 @default.
- W4313238720 cites W3172157954 @default.
- W4313238720 cites W3217740132 @default.
- W4313238720 cites W4224227858 @default.
- W4313238720 cites W4254152438 @default.
- W4313238720 cites W4280634728 @default.
- W4313238720 cites W4285678564 @default.
- W4313238720 cites W4308929210 @default.
- W4313238720 cites W2770878219 @default.
- W4313238720 doi "https://doi.org/10.3390/ph16010046" @default.
- W4313238720 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36678543" @default.
- W4313238720 hasPublicationYear "2022" @default.
- W4313238720 type Work @default.
- W4313238720 citedByCount "2" @default.
- W4313238720 countsByYear W43132387202023 @default.
- W4313238720 crossrefType "journal-article" @default.
- W4313238720 hasAuthorship W4313238720A5038805449 @default.
- W4313238720 hasAuthorship W4313238720A5048473316 @default.
- W4313238720 hasAuthorship W4313238720A5056723526 @default.
- W4313238720 hasAuthorship W4313238720A5069101058 @default.
- W4313238720 hasAuthorship W4313238720A5081158417 @default.
- W4313238720 hasBestOaLocation W43132387201 @default.
- W4313238720 hasConcept C2780035454 @default.
- W4313238720 hasConcept C2992195973 @default.
- W4313238720 hasConcept C55493867 @default.
- W4313238720 hasConcept C60644358 @default.
- W4313238720 hasConcept C70721500 @default.