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- W4313247257 abstract "Periodontitis is one of the most common osteolytic inflammatory diseases in humans. Formation of a periodontal bacteria-associated biofilm is thought to be a trigger for the development of periodontitis, but it is not believed to be sufficient by itself to sustain the disease, as compromise of the host immune response is critical for inflammatory tissue breakdown and disease progression. Macrophages play an important role in the immune response both during the initiation and resolution of the inflammation. Macrophages are broadly classified into two phenotypes, pro-inflammatory M1 and wound-healing M2 cells. Since M2 macrophages contribute to the tissue-remodeling process, effective M2 macrophage induction would provide a favorable environment for resolution of the inflammation and tissue regeneration." @default.
- W4313247257 created "2023-01-06" @default.
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- W4313247257 date "2022-12-28" @default.
- W4313247257 modified "2023-09-25" @default.
- W4313247257 title "Development of a novel therapeutic approach for periodontitis that utilizes GMSCs-derived exosome through induction of M2 macrophage" @default.
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- W4313247257 doi "https://doi.org/10.2329/perio.64.109" @default.
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