FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313251351> ?p ?o ?g. }

• W4313251351 endingPage "e32252" @default.
• W4313251351 startingPage "e32252" @default.
• W4313251351 abstract "Introduction: Albumin-bound paclitaxel (nab-PTX), a novel paclitaxel preparation, has been found to successfully blocks tumor progression in breast and lung cancer. However, at the same time of as clinical application, neurotoxicity caused by nab-PTX has become the main factor limiting the clinical application of nab-PTX, which seriously affects the quality of life of patients and increases their psychological or financial burden. In clinical applications, JHGWD combined with bloodletting therapy at the end of the extremities has a positive effect on neurotoxic symptoms such as numbness, pain, and weakness of the hands and feet caused by nab-PTX. In a single-arm experiment, it was also found that the immediate effective rate of exsanguination therapy was as high as 70%, and when combined with oral Chinese medicine treatment, it further improved the efficacy. Therefore, a randomized controlled trial (RCT) was designed to further evaluate the efficacy and safety of this treatment. Methods: This RCT will be conducted at the Shanxi Provincial Hospital of Traditional Chinese Medicine. A total of 120 patients with Nab-PTX chemotherapy-induced neurotoxicity will be recruited. Treatment groups will be categorized into herbs alone group, bloodletting treatment alone group, and herbs combined with bloodletting group. Blank control was used. The primary outcome will be the EORTC QLQ-CIPN20 scale of the included patients, and the secondary outcomes will include EMG, peripheral neurotoxicity symptom score, NCI-CTCAE5.0 peripheral neurotoxicity grade, and WHO anti-tumor drug peripheral neurotoxicity grade. Adverse reactions will be recorded throughout the process. All data in this RCT will be analyzed by SPSS 26.0 software. Discussion: The results of this RCT will contribute to treating PIPN, relieving the neurotoxic symptoms, and improving the quality of life of patients. Finally, the RCT results will be published in a relevant academic journal on completion of the trial. Trial registration: ChiCTR2200060217(May22,2022)" @default.
• W4313251351 created "2023-01-06" @default.
• W4313251351 creator A5034028862 @default.
• W4313251351 creator A5034140386 @default.
• W4313251351 creator A5037195495 @default.
• W4313251351 creator A5042567804 @default.
• W4313251351 creator A5063447635 @default.
• W4313251351 creator A5070611692 @default.
• W4313251351 creator A5085461218 @default.
• W4313251351 date "2022-12-23" @default.
• W4313251351 modified "2023-09-23" @default.
• W4313251351 title "A randomized controlled study of a combination of internal and external treatments for albumin paclitaxel-related peripheral neurotoxicity: A randomized controlled: A study protocol" @default.
• W4313251351 cites W2060140468 @default.
• W4313251351 cites W2069595796 @default.
• W4313251351 cites W2099321295 @default.
• W4313251351 cites W2145692204 @default.
• W4313251351 cites W2149711855 @default.
• W4313251351 cites W2512959427 @default.
• W4313251351 cites W2518776848 @default.
• W4313251351 cites W2621825389 @default.
• W4313251351 cites W2735699963 @default.
• W4313251351 cites W2750084680 @default.
• W4313251351 cites W2918943168 @default.
• W4313251351 cites W2943444124 @default.
• W4313251351 cites W2991056365 @default.
• W4313251351 cites W2991274658 @default.
• W4313251351 cites W2998890161 @default.
• W4313251351 cites W3043680095 @default.
• W4313251351 cites W3082166173 @default.
• W4313251351 cites W3126229780 @default.
• W4313251351 cites W4206776873 @default.
• W4313251351 cites W4210653950 @default.
• W4313251351 cites W4211078013 @default.
• W4313251351 cites W4212784446 @default.
• W4313251351 cites W4224061283 @default.
• W4313251351 doi "https://doi.org/10.1097/md.0000000000032252" @default.
• W4313251351 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36595835" @default.
• W4313251351 hasPublicationYear "2022" @default.
• W4313251351 type Work @default.
• W4313251351 citedByCount "0" @default.
• W4313251351 crossrefType "journal-article" @default.
• W4313251351 hasAuthorship W4313251351A5034028862 @default.
• W4313251351 hasAuthorship W4313251351A5034140386 @default.
• W4313251351 hasAuthorship W4313251351A5037195495 @default.
• W4313251351 hasAuthorship W4313251351A5042567804 @default.
• W4313251351 hasAuthorship W4313251351A5063447635 @default.
• W4313251351 hasAuthorship W4313251351A5070611692 @default.
• W4313251351 hasAuthorship W4313251351A5085461218 @default.
• W4313251351 hasBestOaLocation W43132513511 @default.
• W4313251351 hasConcept C121608353 @default.
• W4313251351 hasConcept C126322002 @default.
• W4313251351 hasConcept C141071460 @default.
• W4313251351 hasConcept C142724271 @default.
• W4313251351 hasConcept C168563851 @default.
• W4313251351 hasConcept C197934379 @default.
• W4313251351 hasConcept C204787440 @default.
• W4313251351 hasConcept C2776694085 @default.
• W4313251351 hasConcept C2777292972 @default.
• W4313251351 hasConcept C2777511904 @default.
• W4313251351 hasConcept C2779491297 @default.
• W4313251351 hasConcept C29730261 @default.
• W4313251351 hasConcept C530470458 @default.
• W4313251351 hasConcept C56837625 @default.
• W4313251351 hasConcept C61943457 @default.
• W4313251351 hasConcept C71924100 @default.
• W4313251351 hasConceptScore W4313251351C121608353 @default.
• W4313251351 hasConceptScore W4313251351C126322002 @default.
• W4313251351 hasConceptScore W4313251351C141071460 @default.
• W4313251351 hasConceptScore W4313251351C142724271 @default.
• W4313251351 hasConceptScore W4313251351C168563851 @default.
• W4313251351 hasConceptScore W4313251351C197934379 @default.
• W4313251351 hasConceptScore W4313251351C204787440 @default.
• W4313251351 hasConceptScore W4313251351C2776694085 @default.
• W4313251351 hasConceptScore W4313251351C2777292972 @default.
• W4313251351 hasConceptScore W4313251351C2777511904 @default.
• W4313251351 hasConceptScore W4313251351C2779491297 @default.
• W4313251351 hasConceptScore W4313251351C29730261 @default.
• W4313251351 hasConceptScore W4313251351C530470458 @default.
• W4313251351 hasConceptScore W4313251351C56837625 @default.
• W4313251351 hasConceptScore W4313251351C61943457 @default.
• W4313251351 hasConceptScore W4313251351C71924100 @default.
• W4313251351 hasIssue "51" @default.
• W4313251351 hasLocation W43132513511 @default.
• W4313251351 hasLocation W43132513512 @default.
• W4313251351 hasLocation W43132513513 @default.
• W4313251351 hasLocation W43132513514 @default.
• W4313251351 hasOpenAccess W4313251351 @default.
• W4313251351 hasPrimaryLocation W43132513511 @default.
• W4313251351 hasRelatedWork W1964317189 @default.
• W4313251351 hasRelatedWork W1975820693 @default.
• W4313251351 hasRelatedWork W1983679962 @default.
• W4313251351 hasRelatedWork W2101702024 @default.
• W4313251351 hasRelatedWork W2147391349 @default.
• W4313251351 hasRelatedWork W2347784733 @default.
• W4313251351 hasRelatedWork W2410891004 @default.
• W4313251351 hasRelatedWork W2792941486 @default.
• W4313251351 hasRelatedWork W3039292756 @default.
• W4313251351 hasRelatedWork W3041235120 @default.

• next