Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313252430> ?p ?o ?g. }
- W4313252430 endingPage "363" @default.
- W4313252430 startingPage "352" @default.
- W4313252430 abstract "Anemia and iron deficiency have been associated with poor child cognitive development. A key rationale for the prevention of anemia using supplementation with iron has been the benefits to neurodevelopment. However, little causal evidence exists for these gains. We aimed to examine effects of supplementation with iron or multiple micronutrient powders (MNPs) on brain activity measures using resting electroencephalography (EEG). Children included in this neurocognitive substudy were randomly selected from the Benefits and Risks of Iron Supplementation in Children study, a double-blind, double-dummy, individually randomized, parallel-group trial in Bangladesh, in which children, starting at 8 mo of age, received 3 mo of daily iron syrup, MNPs, or placebo. Resting brain activity was recorded using EEG immediately after intervention (month 3) and after a further 9-month follow-up (month 12). We derived EEG band power measures for delta, theta, alpha, and beta frequency bands. Linear regression models were used to compare the effect of each intervention with that of placebo on the outcomes. Data from 412 children at month 3 and 374 at month 12 were analyzed. At baseline, 43.9% were anemic and 26.7% were iron deficient. Immediately after intervention, iron syrup, but not MNPs, increased the mu alpha-band power, a measure that is associated with maturity and the production of motor actions (iron vs. placebo: mean difference = 0.30; 95% CI: 0.11, 0.50 μV2; P = 0.003; false discovery rate adjusted P = 0.015). Despite effects on hemoglobin and iron status, effects were not observed on the posterior alpha, beta, delta, and theta bands, nor were effects sustained at the 9-month follow-up. The effect size for immediate effects on the mu alpha-band power is comparable in magnitude with psychosocial stimulation interventions and poverty reduction strategies. However, overall, we did not find evidence for long-lasting changes in resting EEG power spectra from iron interventions in young Bangladeshi children. This trial was registered at www.anzctr.org.au as ACTRN12617000660381." @default.
- W4313252430 created "2023-01-06" @default.
- W4313252430 creator A5003938266 @default.
- W4313252430 creator A5005030503 @default.
- W4313252430 creator A5011477010 @default.
- W4313252430 creator A5023908603 @default.
- W4313252430 creator A5035882283 @default.
- W4313252430 creator A5043193152 @default.
- W4313252430 creator A5047561190 @default.
- W4313252430 creator A5050220299 @default.
- W4313252430 creator A5060211293 @default.
- W4313252430 creator A5061215429 @default.
- W4313252430 creator A5068979710 @default.
- W4313252430 creator A5075206803 @default.
- W4313252430 creator A5075824580 @default.
- W4313252430 date "2023-01-01" @default.
- W4313252430 modified "2023-10-15" @default.
- W4313252430 title "Supplementation With Iron Syrup or Iron-Containing Multiple Micronutrient Powders Alters Resting Brain Activity in Bangladeshi Children" @default.
- W4313252430 cites W1449283962 @default.
- W4313252430 cites W1758227525 @default.
- W4313252430 cites W1923306089 @default.
- W4313252430 cites W1967457283 @default.
- W4313252430 cites W1969271354 @default.
- W4313252430 cites W1970352521 @default.
- W4313252430 cites W1995404110 @default.
- W4313252430 cites W2002033845 @default.
- W4313252430 cites W2005959980 @default.
- W4313252430 cites W2010454129 @default.
- W4313252430 cites W2019556151 @default.
- W4313252430 cites W2022026095 @default.
- W4313252430 cites W2032730227 @default.
- W4313252430 cites W2035386672 @default.
- W4313252430 cites W2037923840 @default.
- W4313252430 cites W2051055403 @default.
- W4313252430 cites W2066004502 @default.
- W4313252430 cites W2069805138 @default.
- W4313252430 cites W2074583930 @default.
- W4313252430 cites W2078171907 @default.
- W4313252430 cites W2081629711 @default.
- W4313252430 cites W2082752536 @default.
- W4313252430 cites W2086214452 @default.
- W4313252430 cites W2088097018 @default.
- W4313252430 cites W2098330912 @default.
- W4313252430 cites W2104806243 @default.
- W4313252430 cites W2105286705 @default.
- W4313252430 cites W2120290124 @default.
- W4313252430 cites W2125007968 @default.
- W4313252430 cites W2128495200 @default.
- W4313252430 cites W2157368272 @default.
- W4313252430 cites W2164404496 @default.
- W4313252430 cites W2164922756 @default.
- W4313252430 cites W2167322609 @default.
- W4313252430 cites W2171112462 @default.
- W4313252430 cites W2554438339 @default.
- W4313252430 cites W2766248338 @default.
- W4313252430 cites W2768272429 @default.
- W4313252430 cites W2952241844 @default.
- W4313252430 cites W2974582045 @default.
- W4313252430 cites W2981832088 @default.
- W4313252430 cites W2982119322 @default.
- W4313252430 cites W3026741707 @default.
- W4313252430 cites W3028008978 @default.
- W4313252430 cites W3039278607 @default.
- W4313252430 cites W3042170114 @default.
- W4313252430 cites W3089047745 @default.
- W4313252430 cites W3110151578 @default.
- W4313252430 cites W3112876798 @default.
- W4313252430 cites W3176222805 @default.
- W4313252430 cites W3197705117 @default.
- W4313252430 cites W4207040139 @default.
- W4313252430 cites W4225390978 @default.
- W4313252430 cites W4294214781 @default.
- W4313252430 doi "https://doi.org/10.1016/j.tjnut.2022.12.026" @default.
- W4313252430 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36913472" @default.
- W4313252430 hasPublicationYear "2023" @default.
- W4313252430 type Work @default.
- W4313252430 citedByCount "1" @default.
- W4313252430 countsByYear W43132524302023 @default.
- W4313252430 crossrefType "journal-article" @default.
- W4313252430 hasAuthorship W4313252430A5003938266 @default.
- W4313252430 hasAuthorship W4313252430A5005030503 @default.
- W4313252430 hasAuthorship W4313252430A5011477010 @default.
- W4313252430 hasAuthorship W4313252430A5023908603 @default.
- W4313252430 hasAuthorship W4313252430A5035882283 @default.
- W4313252430 hasAuthorship W4313252430A5043193152 @default.
- W4313252430 hasAuthorship W4313252430A5047561190 @default.
- W4313252430 hasAuthorship W4313252430A5050220299 @default.
- W4313252430 hasAuthorship W4313252430A5060211293 @default.
- W4313252430 hasAuthorship W4313252430A5061215429 @default.
- W4313252430 hasAuthorship W4313252430A5068979710 @default.
- W4313252430 hasAuthorship W4313252430A5075206803 @default.
- W4313252430 hasAuthorship W4313252430A5075824580 @default.
- W4313252430 hasBestOaLocation W43132524301 @default.
- W4313252430 hasConcept C118552586 @default.
- W4313252430 hasConcept C126322002 @default.
- W4313252430 hasConcept C142724271 @default.
- W4313252430 hasConcept C14522933 @default.
- W4313252430 hasConcept C169900460 @default.