FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313252611> ?p ?o ?g. }

• W4313252611 endingPage "103309" @default.
• W4313252611 startingPage "103309" @default.
• W4313252611 abstract "Chronic back pain (CBP) has extensive clinical and social implications for its sufferers and is a major source of disability. Chronic pain has previously been shown to have central neural factors underpinning it, including the loss of white matter (WM), however traditional methods of analyzing WM microstructure have produced mixed and unclear results. To better understand these factors, we assessed the WM microstructure of 50 patients and 40 healthy controls (HC) using diffusion-weighted imaging. The data were analyzed using fixel-based analysis (FBA), a higher-order diffusion modelling technique applied to CBP for the first time here. Subjects also answered questionnaires relating to pain, disability, catastrophizing, and mood disorders, to establish the relationship between fixelwise metrics and clinical symptoms. FBA determined that, compared to HC, CBP patients had: 1) lower fibre density (FD) in several tracts, specifically the right anterior and bilateral superior thalamic radiations, right spinothalamic tract, right middle cerebellar peduncle, and the body and splenium of corpus callosum; 2) higher FD in the genu of corpus callosum; and 3) lower FDC - a combined fibre density and cross-section measure - in the bilateral spinothalamic tracts and right anterior thalamic radiation. Exploratory correlations showed strong negative relationships between fixelwise metrics and clinical questionnaire scores, especially pain catastrophizing. These results have important implications for the intake and processing of sensory data in CBP that warrant further investigation." @default.
• W4313252611 created "2023-01-06" @default.
• W4313252611 creator A5004327876 @default.
• W4313252611 creator A5046122240 @default.
• W4313252611 creator A5081682823 @default.
• W4313252611 date "2023-01-01" @default.
• W4313252611 modified "2023-10-14" @default.
• W4313252611 title "White matter microstructure predicts measures of clinical symptoms in chronic back pain patients" @default.
• W4313252611 cites W1553266435 @default.
• W4313252611 cites W1565670747 @default.
• W4313252611 cites W1580122521 @default.
• W4313252611 cites W1962885651 @default.
• W4313252611 cites W1970832311 @default.
• W4313252611 cites W1984144008 @default.
• W4313252611 cites W1984453610 @default.
• W4313252611 cites W1995138343 @default.
• W4313252611 cites W2000002132 @default.
• W4313252611 cites W2001611992 @default.
• W4313252611 cites W2010125850 @default.
• W4313252611 cites W2023687307 @default.
• W4313252611 cites W2025513503 @default.
• W4313252611 cites W2027409384 @default.
• W4313252611 cites W2029985169 @default.
• W4313252611 cites W2030123928 @default.
• W4313252611 cites W2039686313 @default.
• W4313252611 cites W2043567003 @default.
• W4313252611 cites W2046372614 @default.
• W4313252611 cites W2047152236 @default.
• W4313252611 cites W2053580438 @default.
• W4313252611 cites W2054002773 @default.
• W4313252611 cites W2060360760 @default.
• W4313252611 cites W2063001897 @default.
• W4313252611 cites W2066396738 @default.
• W4313252611 cites W2068328649 @default.
• W4313252611 cites W2075738639 @default.
• W4313252611 cites W2077240096 @default.
• W4313252611 cites W2077891011 @default.
• W4313252611 cites W2078001618 @default.
• W4313252611 cites W2080108438 @default.
• W4313252611 cites W2082456105 @default.
• W4313252611 cites W2085247866 @default.
• W4313252611 cites W2091696767 @default.
• W4313252611 cites W2093917720 @default.
• W4313252611 cites W2097408032 @default.
• W4313252611 cites W2102747343 @default.
• W4313252611 cites W2107522141 @default.
• W4313252611 cites W2108409682 @default.
• W4313252611 cites W2111575415 @default.
• W4313252611 cites W2112111016 @default.
• W4313252611 cites W2113712314 @default.
• W4313252611 cites W2123569370 @default.
• W4313252611 cites W2125868297 @default.
• W4313252611 cites W2126059053 @default.
• W4313252611 cites W2127967744 @default.
• W4313252611 cites W2130113356 @default.
• W4313252611 cites W2135235221 @default.
• W4313252611 cites W2136145485 @default.
• W4313252611 cites W2137517639 @default.
• W4313252611 cites W2137679584 @default.
• W4313252611 cites W2138407894 @default.
• W4313252611 cites W2159865397 @default.
• W4313252611 cites W2160662805 @default.
• W4313252611 cites W2162723250 @default.
• W4313252611 cites W2165020904 @default.
• W4313252611 cites W2168189344 @default.
• W4313252611 cites W2177917702 @default.
• W4313252611 cites W2302534419 @default.
• W4313252611 cites W2320790765 @default.
• W4313252611 cites W2345555088 @default.
• W4313252611 cites W2346872235 @default.
• W4313252611 cites W2398153550 @default.
• W4313252611 cites W239929985 @default.
• W4313252611 cites W2470259419 @default.
• W4313252611 cites W2520744072 @default.
• W4313252611 cites W2560693837 @default.
• W4313252611 cites W2592523719 @default.
• W4313252611 cites W2604834320 @default.
• W4313252611 cites W2702360522 @default.
• W4313252611 cites W2757556887 @default.
• W4313252611 cites W2765975204 @default.
• W4313252611 cites W2772913187 @default.
• W4313252611 cites W2778340997 @default.
• W4313252611 cites W2789545474 @default.
• W4313252611 cites W2791758041 @default.
• W4313252611 cites W2893129822 @default.
• W4313252611 cites W2962681100 @default.
• W4313252611 cites W2968783567 @default.
• W4313252611 cites W2977883299 @default.
• W4313252611 cites W2996998795 @default.
• W4313252611 cites W3008448137 @default.
• W4313252611 cites W3016452107 @default.
• W4313252611 cites W3048090859 @default.
• W4313252611 cites W3059885064 @default.
• W4313252611 cites W3088728054 @default.
• W4313252611 cites W3093224475 @default.
• W4313252611 cites W3128515524 @default.
• W4313252611 cites W3143397989 @default.
• W4313252611 cites W3153313896 @default.

• next