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• W4313253674 endingPage "422" @default.
• W4313253674 startingPage "409" @default.
• W4313253674 abstract "Heart transplantation (HT) remains the preferred therapy for patients with advanced heart failure. However, for sensitized HT candidates who have antibodies to human leukocyte antigens , finding a suitable donor can be challenging and can lead to adverse waitlist outcomes. In recent years, the number of sensitized patients awaiting HT has increased likely due to the use of durable and mechanical circulatory support as well as increasing number of candidates with underlying congenital heart disease. This State-of-the-Art review discusses the assessment of human leukocyte antigens antibodies, potential desensitization strategies including mechanisms of action and specific protocols, the approach to a potential donor including the use of complement-dependent cytotoxicity, flow cytometry, and virtual crossmatches, and peritransplant induction management." @default.
• W4313253674 created "2023-01-06" @default.
• W4313253674 creator A5000222961 @default.
• W4313253674 creator A5001620639 @default.
• W4313253674 creator A5011986787 @default.
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• W4313253674 creator A5042628496 @default.
• W4313253674 creator A5049320403 @default.
• W4313253674 creator A5065002546 @default.
• W4313253674 creator A5087709436 @default.
• W4313253674 date "2023-04-01" @default.
• W4313253674 modified "2023-09-26" @default.
• W4313253674 title "Detection and management of HLA sensitization in candidates for adult heart transplantation" @default.
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