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- W4313255295 abstract "La ponction biopsie hépatique est un examen pertinent pour déterminer le diagnostic et le pronostic au cours de la prise en charge d’un enfant pour une cholestase persistante. L’échographie abdominale permet d’orienter vers l’origine intra- ou extrahépatique de la cholestase, base des étiologies. Si le diagnostic d’atrésie des voies biliaires, urgence diagnostique, ne requiert classiquement pas d’examen biopsique, le diagnostic de la plupart des autres hypothèses diagnostiques de cholestase intrahépatique nécessite la réalisation d’une biopsie hépatique dont l’analyse histopathologique est souvent associée à des analyses moléculaires complémentaires. Liver biopsy remains the cornerstone of assessment for determining the diagnosis and prognosis during the management of a child with persistent cholestasis. Abdominal ultrasonography can be used to explore the intra- or extrahepatic origin of the cholestasis, which is the basis of the etiological hypothesis. While the diagnosis of biliary atresia, a diagnostic emergency, does not usually require any biopsy, diagnosis of most forms of intrahepatic cholestasis is facilitated by liver biopsy and by co-ordination of histopathological study with next-generation sequencing analysis." @default.
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- W4313255295 date "2023-01-01" @default.
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- W4313255295 title "Biopsie hépatique dans la prise en charge des cholestases de l’enfant" @default.
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- W4313255295 doi "https://doi.org/10.1016/s1773-035x(22)00405-1" @default.
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