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- W4313255385 abstract "Antibody-mediated rejection (ABMR) results from a pro-inflammatory cascade that occurs following the binding of circulating anti-HLA antibodies to HLA on donor endothelial cells. As such, pathogenic pathways of humoral immunity are considered key targets for diagnostic and therapeutic focus. As one example, antibody-dependent cell-mediated cytotoxicity (ADCC) is an important mechanism of ABMR, in which graft-bound anti-HLA antibodies activate innate leukocytes such as natural killer (NK) cells and monocytes via surface Fc gamma receptors for IgG1." @default.
- W4313255385 created "2023-01-06" @default.
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- W4313255385 date "2023-03-01" @default.
- W4313255385 modified "2023-10-18" @default.
- W4313255385 title "Natural killer cells, CMV infection, and antibody-mediated rejection" @default.
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- W4313255385 doi "https://doi.org/10.1016/j.healun.2022.12.017" @default.
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