FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313255428> ?p ?o ?g. }

• W4313255428 endingPage "108683" @default.
• W4313255428 startingPage "108683" @default.
• W4313255428 abstract "Beyond reduced audibility, there is convincing evidence that the auditory system adapts according to the principles of homeostatic plasticity in response to a hearing loss. Such compensatory changes include modulation of central auditory gain mechanisms. Earplugging is a common experimental method that has been used to introduce a temporary, reversible hearing loss that induces changes consistent with central gain modulation. In the present study, young, normal-hearing adult participants wore a unilateral earplug for two weeks, during which we measured changes in the acoustic reflex threshold (ART), loudness perception, and cortically-evoked (40 Hz) auditory steady-state response (ASSR) to assess potential modulation in central gain with reduced peripheral input. The ART decreased on average by 8 to 10 dB during the treatment period, with modest increases in loudness perception after one week but not after two weeks of earplug use. Significant changes in both the magnitude and hemispheric laterality of source-localized cortical ASSR measures revealed asymmetrical changes in stimulus-driven cortical activity over time. The ART results following unilateral earplugging are consistent with the literature and suggest that homeostatic plasticity is evident in the brainstem. The novel findings from the cortical ASSR in the present study indicates that reduced peripheral input induces adaptive homeostatic plasticity reflected as both an increase in central gain in the auditory brainstem and reduced cortical activity ipsilateral to the deprived ear. Both the ART and the novel use of the 40-Hz ASSR provide sensitive measures of central gain modulation in the brainstem and cortex of young, normal hearing listeners, and thus may be useful in future studies with other clinical populations." @default.
• W4313255428 created "2023-01-06" @default.
• W4313255428 creator A5002386870 @default.
• W4313255428 creator A5033368361 @default.
• W4313255428 creator A5033662713 @default.
• W4313255428 creator A5049470385 @default.
• W4313255428 creator A5064684693 @default.
• W4313255428 creator A5083554074 @default.
• W4313255428 date "2023-02-01" @default.
• W4313255428 modified "2023-09-24" @default.
• W4313255428 title "Acoustic deprivation modulates central gain in human auditory brainstem and cortex" @default.
• W4313255428 cites W1543088917 @default.
• W4313255428 cites W1600409999 @default.
• W4313255428 cites W1928595707 @default.
• W4313255428 cites W1966004596 @default.
• W4313255428 cites W1967759478 @default.
• W4313255428 cites W1970303222 @default.
• W4313255428 cites W1975006259 @default.
• W4313255428 cites W1976359337 @default.
• W4313255428 cites W1977505553 @default.
• W4313255428 cites W1983973777 @default.
• W4313255428 cites W1987154696 @default.
• W4313255428 cites W1988166898 @default.
• W4313255428 cites W1988279885 @default.
• W4313255428 cites W1991604810 @default.
• W4313255428 cites W1992030476 @default.
• W4313255428 cites W1994509877 @default.
• W4313255428 cites W2007581301 @default.
• W4313255428 cites W2013150886 @default.
• W4313255428 cites W2014502281 @default.
• W4313255428 cites W2017792517 @default.
• W4313255428 cites W2025261473 @default.
• W4313255428 cites W2030648422 @default.
• W4313255428 cites W2033253604 @default.
• W4313255428 cites W2034537853 @default.
• W4313255428 cites W2035662010 @default.
• W4313255428 cites W2038262310 @default.
• W4313255428 cites W2041064197 @default.
• W4313255428 cites W2041245333 @default.
• W4313255428 cites W2046656987 @default.
• W4313255428 cites W2049236307 @default.
• W4313255428 cites W2056829537 @default.
• W4313255428 cites W2058338014 @default.
• W4313255428 cites W2058817275 @default.
• W4313255428 cites W2059837297 @default.
• W4313255428 cites W2062526841 @default.
• W4313255428 cites W2062876788 @default.
• W4313255428 cites W2063062105 @default.
• W4313255428 cites W2064504453 @default.
• W4313255428 cites W2068334533 @default.
• W4313255428 cites W2071310824 @default.
• W4313255428 cites W2072699251 @default.
• W4313255428 cites W2074494951 @default.
• W4313255428 cites W2079659716 @default.
• W4313255428 cites W2083708779 @default.
• W4313255428 cites W2084749103 @default.
• W4313255428 cites W2087390900 @default.
• W4313255428 cites W2089710786 @default.
• W4313255428 cites W2092151119 @default.
• W4313255428 cites W2098281817 @default.
• W4313255428 cites W2099193444 @default.
• W4313255428 cites W2099801199 @default.
• W4313255428 cites W2103551437 @default.
• W4313255428 cites W2104466105 @default.
• W4313255428 cites W2107781710 @default.
• W4313255428 cites W2115900486 @default.
• W4313255428 cites W2128684830 @default.
• W4313255428 cites W2141497247 @default.
• W4313255428 cites W2145309136 @default.
• W4313255428 cites W2148398429 @default.
• W4313255428 cites W2150469050 @default.
• W4313255428 cites W2160426524 @default.
• W4313255428 cites W2165758561 @default.
• W4313255428 cites W2199388024 @default.
• W4313255428 cites W2233813774 @default.
• W4313255428 cites W2264170165 @default.
• W4313255428 cites W2269259465 @default.
• W4313255428 cites W2401964813 @default.
• W4313255428 cites W2520061816 @default.
• W4313255428 cites W2525092117 @default.
• W4313255428 cites W2526247294 @default.
• W4313255428 cites W2555661329 @default.
• W4313255428 cites W2577451197 @default.
• W4313255428 cites W2578163850 @default.
• W4313255428 cites W2591749336 @default.
• W4313255428 cites W2592361227 @default.
• W4313255428 cites W2593149636 @default.
• W4313255428 cites W2650156602 @default.
• W4313255428 cites W2772644194 @default.
• W4313255428 cites W2786090555 @default.
• W4313255428 cites W2791708697 @default.
• W4313255428 cites W2799731195 @default.
• W4313255428 cites W2805379203 @default.
• W4313255428 cites W2896666126 @default.
• W4313255428 cites W2913559870 @default.
• W4313255428 cites W2916338762 @default.
• W4313255428 cites W2921038291 @default.
• W4313255428 cites W2921331502 @default.

• next