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• W4313260060 abstract "Bisphenol A (BPA) is a widely produced chemical worldwide found in numerous everyday products. Its endocrine-disrupting properties and omnipresence have aroused concern and led to several restrictions on its use. These restrictions and growing public awareness about the toxicity of BPA have resulted in market products labeled BPA-free, with BPAs often being replaced by other bisphenols. This is why constant biomonitoring of bisphenol levels in various body fluids and tissues is essential. In this study, we propose the use of simple, cost-effective high-performance liquid chromatography coupled with the fluorescence detector (HPLC-FLD) method for the determination of simultaneously selected bisphenols in amniotic fluid. For the sample preparation, a fast, simple, and green dispersive liquid-liquid microextraction (DLLME) method was used, achieving mean recovery values in the range of 80.9-115.9% with relative standard deviations below 12% for all analytes. Limits of quantification (LOQs) determined in the amniotic fluid matrix ranged from 6.17 to 22.72 ng/mL and were obtained from a calibration curve constructed using least-squares linear regression analysis for all cases. The presented sample preparation procedure can be easily adopted for LC-MS analysis." @default.
• W4313260060 created "2023-01-06" @default.
• W4313260060 creator A5010626761 @default.
• W4313260060 creator A5086901859 @default.
• W4313260060 date "2022-12-24" @default.
• W4313260060 modified "2023-10-16" @default.
• W4313260060 title "Application of High-Performance Liquid Chromatography Combined with Fluorescence Detector and Dispersive Liquid–Liquid Microextraction to Quantification of Selected Bisphenols in Human Amniotic Fluid Samples" @default.
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• W4313260060 doi "https://doi.org/10.3390/ijerph20010297" @default.
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