FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313261946> ?p ?o ?g. }

• W4313261946 abstract "Abstract Introduction Neonatal sepsis is a major cause of morbidity and mortality with a higher burden from the low- and middle-income countries. The coronavirus disease 2019 (Covid 19) pandemic has impacted healthcare in various ways including healthcare-associated infections (HAI). The objective of the present study was to determine changes in organism profile and incidence rates of HAI in neonates admitted to the index hospital during the pandemic and compared it with the data from the pre-pandemic period. Materials and methods The study design was a retrospective, observational analysis of data from neonates with culture-positive sepsis, in a tertiary care children’s hospital, between January 2018 and December 2021. Pre-Covid (January 2018 to December 2019) and Covid period data (January 2020 to December 2021) were analyzed for the significance of change. Results The prevalence of culture-positive sepsis, in pre-Covid and Covid periods, was 19.55% [95% confidence interval (95% CI) 17.13–21.52)] and 18.36% (CI 16.05–20.74), respectively. HAI rates/1000 patient days increased slightly during the Covid pandemic [7.2% (95% CI 6.98–10.08) to 9.8% (95% CI 9.78–13.67)] mainly due to an increase in fungal HAI (26% pre- vs. 41.5% Covid period). However, the proportion of Gram-negative (GN) infections fell significantly (70.5% vs. 48.6%) during the same period. In the pre-Covid period, Klebsiella followed by Burkholderia cepacia, Acinetobacter spp and Pseudomonas, were the major HAI isolates. During the Covid period, there was a decline in these isolates and Burkholderia spp was not detected. All fungal isolates were Candida species. The case fatality ratio (CFR) from HAI decreased significantly from 38% to 15.45%, mainly due to a decrease in GN HAI. Conclusion During Covid pandemic, there was a significant decline in GN HAI and CFR from HAI, due to improved compliance with infection control measures in the neonatal intensive care unit (NICU). At the same time, there was a rise in the fungal HAI, possibly because of a higher proportion of premature, and sick neonates with longer hospital stay and more invasive procedures. Consolidations of gains in infection control and restriction of invasive procedures could help to minimize HAI in NICUs." @default.
• W4313261946 created "2023-01-06" @default.
• W4313261946 creator A5052550882 @default.
• W4313261946 creator A5055249717 @default.
• W4313261946 creator A5064149984 @default.
• W4313261946 creator A5075967215 @default.
• W4313261946 date "2022-12-05" @default.
• W4313261946 modified "2023-10-18" @default.
• W4313261946 title "Covid-period-associated changes in organism profile of neonatal sepsis in a tertiary center from East India" @default.
• W4313261946 cites W1972281961 @default.
• W4313261946 cites W2168581177 @default.
• W4313261946 cites W2752261284 @default.
• W4313261946 cites W2810571275 @default.
• W4313261946 cites W2912065765 @default.
• W4313261946 cites W2995923153 @default.
• W4313261946 cites W3008670120 @default.
• W4313261946 cites W3011337716 @default.
• W4313261946 cites W3047823725 @default.
• W4313261946 cites W3128769337 @default.
• W4313261946 cites W3163819161 @default.
• W4313261946 cites W3174598031 @default.
• W4313261946 cites W4226342251 @default.
• W4313261946 doi "https://doi.org/10.1093/tropej/fmac106" @default.
• W4313261946 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36579931" @default.
• W4313261946 hasPublicationYear "2022" @default.
• W4313261946 type Work @default.
• W4313261946 citedByCount "1" @default.
• W4313261946 countsByYear W43132619462023 @default.
• W4313261946 crossrefType "journal-article" @default.
• W4313261946 hasAuthorship W4313261946A5052550882 @default.
• W4313261946 hasAuthorship W4313261946A5055249717 @default.
• W4313261946 hasAuthorship W4313261946A5064149984 @default.
• W4313261946 hasAuthorship W4313261946A5075967215 @default.
• W4313261946 hasConcept C120665830 @default.
• W4313261946 hasConcept C121332964 @default.
• W4313261946 hasConcept C126322002 @default.
• W4313261946 hasConcept C167135981 @default.
• W4313261946 hasConcept C187212893 @default.
• W4313261946 hasConcept C2775953899 @default.
• W4313261946 hasConcept C2778384902 @default.
• W4313261946 hasConcept C2779134260 @default.
• W4313261946 hasConcept C3008058167 @default.
• W4313261946 hasConcept C44249647 @default.
• W4313261946 hasConcept C524204448 @default.
• W4313261946 hasConcept C61511704 @default.
• W4313261946 hasConcept C71924100 @default.
• W4313261946 hasConcept C89623803 @default.
• W4313261946 hasConceptScore W4313261946C120665830 @default.
• W4313261946 hasConceptScore W4313261946C121332964 @default.
• W4313261946 hasConceptScore W4313261946C126322002 @default.
• W4313261946 hasConceptScore W4313261946C167135981 @default.
• W4313261946 hasConceptScore W4313261946C187212893 @default.
• W4313261946 hasConceptScore W4313261946C2775953899 @default.
• W4313261946 hasConceptScore W4313261946C2778384902 @default.
• W4313261946 hasConceptScore W4313261946C2779134260 @default.
• W4313261946 hasConceptScore W4313261946C3008058167 @default.
• W4313261946 hasConceptScore W4313261946C44249647 @default.
• W4313261946 hasConceptScore W4313261946C524204448 @default.
• W4313261946 hasConceptScore W4313261946C61511704 @default.
• W4313261946 hasConceptScore W4313261946C71924100 @default.
• W4313261946 hasConceptScore W4313261946C89623803 @default.
• W4313261946 hasIssue "1" @default.
• W4313261946 hasLocation W43132619461 @default.
• W4313261946 hasLocation W43132619462 @default.
• W4313261946 hasOpenAccess W4313261946 @default.
• W4313261946 hasPrimaryLocation W43132619461 @default.
• W4313261946 hasRelatedWork W13777102 @default.
• W4313261946 hasRelatedWork W1972040355 @default.
• W4313261946 hasRelatedWork W2330716163 @default.
• W4313261946 hasRelatedWork W2416395208 @default.
• W4313261946 hasRelatedWork W2608873815 @default.
• W4313261946 hasRelatedWork W2791224638 @default.
• W4313261946 hasRelatedWork W2913564985 @default.
• W4313261946 hasRelatedWork W2987440412 @default.
• W4313261946 hasRelatedWork W3026474175 @default.
• W4313261946 hasRelatedWork W4200400602 @default.
• W4313261946 hasVolume "69" @default.
• W4313261946 isParatext "false" @default.
• W4313261946 isRetracted "false" @default.
• W4313261946 workType "article" @default.