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- W4313263332 abstract "Delirium is an acute, transient, and usually reversible alteration in cognition, characterized by fluctuations in attention, confusion, disorientation, and sometimes hallucinations/paranoia. Special care should be used when treating this condition in the Pediatric population. In this case, we discuss an adolescent patient with a history of multiorgan transplant who developed delirium shortly following hospitalization for dehydrating diarrhea and acute kidney injury, then complicated by hepatic encephalopathy, new onset-seizures and frontal lobe infarcts. Minimal evidence exists to guide treatment of delirium in such medically complex Pediatric populations and there are no FDA-approved treatments for Pediatric delirium. We discuss his clinical course during the treatment of his delirium, rationale and indications for pharmacologic interventions, and implications for future practice regarding the treatment of pediatric delirium in medically complex patients. We used multiple psychiatric assessments, delirium assessment tools, and collateral from hospital staff to determine our patient's level of delirium on a daily basis. After the initiation of Quetiapine, the patient's delirium symptoms improved over the course of multiple weeks. Quetiapine proved to be effective in treating our patient's delirium, even in the setting of continued surgical and procedural interventions. Despite minimal yet emerging evidence, it may be necessary to treat impairing symptoms such as agitation or delusions/illusions if the delirium is preventing medical correction of its underlying cause." @default.
- W4313263332 created "2023-01-06" @default.
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- W4313263332 date "2023-06-01" @default.
- W4313263332 modified "2023-10-14" @default.
- W4313263332 title "Management of Pediatric Delirium in the Setting of Hepatic Encephalopathy" @default.
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- W4313263332 doi "https://doi.org/10.1016/j.psycr.2022.100095" @default.
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