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- W4313269194 abstract "We performed a meta-analysis to examine the effect of oral curcumin on serum levels of creatinine and blood urea nitrogen (BUN). Using four databases, a systematic search was performed up to May 2022 using relevant keywords. To analyze the impact of combined trials, we applied the weighted mean difference (WMD) in a random-effects model. In total, 14 studies were included in the meta-analysis. We found an overall significant effect of oral curcumin supplementation on improved creatinine (WMD: −0.08, 95 % CI: −0.14, −0.03 mg/dL; P = 0.004). Serum levels of BUN increased following curcumin supplementation (WMD: 0.41, 95 % CI: −0.23, 1.05 mg/dL; P < 0.001). In the subgroup analysis, curcumin showed significantly favorable effects on serum BUN in trials with longer duration of curcumin intervention. Oral curcumin with high bioavailability has a positive impact on serum levels of creatinine and BUN when supplemented for > 8 weeks in patients with inflammatory diseases." @default.
- W4313269194 created "2023-01-06" @default.
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- W4313269194 date "2023-01-01" @default.
- W4313269194 modified "2023-10-14" @default.
- W4313269194 title "The effect of curcumin supplementation on renal function: A systematic and meta-analysis of randomized controlled trials" @default.
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- W4313269194 doi "https://doi.org/10.1016/j.jff.2022.105396" @default.
- W4313269194 hasPublicationYear "2023" @default.
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