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- W4313271946 abstract "Introduction: Targeted temperature management (TTM) has shown promise in improving survival to hospital discharge and neurologic outcomes. Analysis of large nationwide datasets indicated that cancer patients who sustained cardiopulmonary arrest were less likely to receive post-arrest procedures and survive to hospital discharge. However, more granular cancer related data is lacking, thus, we retrospectively analyzed TTM in post-cardiac arrest cancer patients. Methods: Single center study at a tertiary cancer center evaluating TTM in patients who suffered cardiopulmonary arrest between January 2017 and April 2022. At provider discretion, patients were cooled with the Arctic Sun to 33°C or 36°C. Results: Four percent of patients (22/531) underwent TTM during the study period. The median age was 70 and 63% were male. 90% of patients had solid tumors, 68% had metastatic disease and 27% were surgical patients. Median interval time from cancer diagnosis to CPR was 2 years with median interval time from last cancer directed treatment to CPR being 6 days. 82% of all patients had CPR outside the ICU and 95% had non-shockable rhythms. The median duration of CPR was 9.5 minutes. Median interval time to electronic TTM order was 1.5 hrs, median interval to achieve target temperature was 3.2 hrs and median duration of TTM was 16.3 hrs. 95% of patients achieved their target temperature with 82% achieving 36⁰C and 18% achieving 33⁰C. Twenty-seven percent (6/22) survived to hospital discharge - all with solid tumor cancer, one with a shockable rhythm. Two were discharged to home hospice and 4 were discharged to SNF/SAR. At discharge, the average Modified Rankin Score was 4.6. Currently, 1 patient is receiving active cancer directed treatment and 1 has returned to prior functional status. The remaining two patients expired shortly after transfer to SNF/SAR. Conclusions: Overall, our study demonstrated that post-cardiac arrest care in an oncologic population is feasible. The rate of TTM at our institution was in line with retrospective observational analyses that have showed 2-13% of in-hospital cardiac arrest patients receive TTM. With increasing rates of cancer survivorship and high prevalence of cardiovascular disease, further studies in TTM in oncology patients post-cardiac arrest are necessary." @default.
- W4313271946 created "2023-01-06" @default.
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- W4313271946 date "2022-12-15" @default.
- W4313271946 modified "2023-09-25" @default.
- W4313271946 title "138: TARGETED TEMPERATURE IN POST-ARREST CARE FOR CANCER PATIENTS" @default.
- W4313271946 doi "https://doi.org/10.1097/01.ccm.0000906288.41557.61" @default.
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