Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313279013> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W4313279013 endingPage "721" @default.
- W4313279013 startingPage "713" @default.
- W4313279013 abstract "In current renal transplant pathology practice, interstitial fibrosis is visually assessed in categories according to the Banff classification. As this has a moderate reproducibility, which is little ameliorated by morphometric analysis, we investigated whether visual renal fibrosis assessment is feasible on a continuous scale, i.e. as a percentage of affected area of the cortex.Protocol renal biopsies taken at transplantation (n = 125), three (n = 73) and 12 months (n = 88) after transplantation were visually scored in categories (Banff) and percentages for interstitial fibrosis (ci). Interobserver variation (ICC and weighted κ) was assessed, and morphometric analysis on Sirius red-stained sections was performed. Correlations between the different methods and their association with donor age and eGFR 1 and 5 years post-transplant were analysed using Pearson's or Spearman's rho. Interobserver agreement was equivalent for Banff and %ci (κ = 0.713 versus ICC = 0.792), and for Banff IF/TA and %IF/TA (κ = 0.615 versus ICC = 0.743). Both Banff and %ci were associated with Sirius red morphometry in 3 and 12 months. With all three methods, a significant correlation was found between donor age and fibrosis in the implantation biopsy and between fibrosis in the 12 months' biopsy and eGFR at 1 and 5 years (eGFR at 1 year: Sirius red ρ = 0.487, %ci ρ = 0.393, Banff ρ = 0.413, all P < 0.01, eGFR at 5 years: Sirius red ρ = 0.392, %ci ρ = 0.333, Banff ρ = 0.435, all P < 0.01).Interstitial fibrosis assessment on a continuous scale can be used next to scoring in categories according to the Banff classification in protocol renal transplant biopsies." @default.
- W4313279013 created "2023-01-06" @default.
- W4313279013 creator A5009368932 @default.
- W4313279013 creator A5011705362 @default.
- W4313279013 creator A5026198066 @default.
- W4313279013 creator A5034910497 @default.
- W4313279013 creator A5042277620 @default.
- W4313279013 creator A5050861541 @default.
- W4313279013 creator A5058568469 @default.
- W4313279013 creator A5089149809 @default.
- W4313279013 date "2023-01-30" @default.
- W4313279013 modified "2023-10-17" @default.
- W4313279013 title "Visual interstitial fibrosis assessment as continuous variable in protocol renal transplant biopsies" @default.
- W4313279013 cites W1566835344 @default.
- W4313279013 cites W1678933000 @default.
- W4313279013 cites W1966762328 @default.
- W4313279013 cites W1973645636 @default.
- W4313279013 cites W1983275136 @default.
- W4313279013 cites W1995791071 @default.
- W4313279013 cites W2045946643 @default.
- W4313279013 cites W2091942988 @default.
- W4313279013 cites W2094113221 @default.
- W4313279013 cites W2124720938 @default.
- W4313279013 cites W2126677023 @default.
- W4313279013 cites W2127999688 @default.
- W4313279013 cites W2133956667 @default.
- W4313279013 cites W2136813012 @default.
- W4313279013 cites W2142088870 @default.
- W4313279013 cites W2152118565 @default.
- W4313279013 cites W2155965977 @default.
- W4313279013 cites W2162101359 @default.
- W4313279013 cites W2464822802 @default.
- W4313279013 cites W2560324947 @default.
- W4313279013 cites W2745494719 @default.
- W4313279013 cites W2808825376 @default.
- W4313279013 cites W2972214324 @default.
- W4313279013 cites W3020579886 @default.
- W4313279013 cites W3080446999 @default.
- W4313279013 cites W3089623907 @default.
- W4313279013 cites W3176130680 @default.
- W4313279013 doi "https://doi.org/10.1111/his.14857" @default.
- W4313279013 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36579371" @default.
- W4313279013 hasPublicationYear "2023" @default.
- W4313279013 type Work @default.
- W4313279013 citedByCount "0" @default.
- W4313279013 crossrefType "journal-article" @default.
- W4313279013 hasAuthorship W4313279013A5009368932 @default.
- W4313279013 hasAuthorship W4313279013A5011705362 @default.
- W4313279013 hasAuthorship W4313279013A5026198066 @default.
- W4313279013 hasAuthorship W4313279013A5034910497 @default.
- W4313279013 hasAuthorship W4313279013A5042277620 @default.
- W4313279013 hasAuthorship W4313279013A5050861541 @default.
- W4313279013 hasAuthorship W4313279013A5058568469 @default.
- W4313279013 hasAuthorship W4313279013A5089149809 @default.
- W4313279013 hasBestOaLocation W43132790131 @default.
- W4313279013 hasConcept C126322002 @default.
- W4313279013 hasConcept C126894567 @default.
- W4313279013 hasConcept C142724271 @default.
- W4313279013 hasConcept C2775934546 @default.
- W4313279013 hasConcept C2779770810 @default.
- W4313279013 hasConcept C2780303639 @default.
- W4313279013 hasConcept C2780559512 @default.
- W4313279013 hasConcept C2911091166 @default.
- W4313279013 hasConcept C71924100 @default.
- W4313279013 hasConceptScore W4313279013C126322002 @default.
- W4313279013 hasConceptScore W4313279013C126894567 @default.
- W4313279013 hasConceptScore W4313279013C142724271 @default.
- W4313279013 hasConceptScore W4313279013C2775934546 @default.
- W4313279013 hasConceptScore W4313279013C2779770810 @default.
- W4313279013 hasConceptScore W4313279013C2780303639 @default.
- W4313279013 hasConceptScore W4313279013C2780559512 @default.
- W4313279013 hasConceptScore W4313279013C2911091166 @default.
- W4313279013 hasConceptScore W4313279013C71924100 @default.
- W4313279013 hasFunder F4320321643 @default.
- W4313279013 hasIssue "5" @default.
- W4313279013 hasLocation W43132790131 @default.
- W4313279013 hasLocation W43132790132 @default.
- W4313279013 hasOpenAccess W4313279013 @default.
- W4313279013 hasPrimaryLocation W43132790131 @default.
- W4313279013 hasRelatedWork W1977755133 @default.
- W4313279013 hasRelatedWork W2055890431 @default.
- W4313279013 hasRelatedWork W2063513203 @default.
- W4313279013 hasRelatedWork W2087086071 @default.
- W4313279013 hasRelatedWork W2116100577 @default.
- W4313279013 hasRelatedWork W2117376546 @default.
- W4313279013 hasRelatedWork W2138147133 @default.
- W4313279013 hasRelatedWork W2370413994 @default.
- W4313279013 hasRelatedWork W3032663059 @default.
- W4313279013 hasRelatedWork W4308596770 @default.
- W4313279013 hasVolume "82" @default.
- W4313279013 isParatext "false" @default.
- W4313279013 isRetracted "false" @default.
- W4313279013 workType "article" @default.