Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313280070> ?p ?o ?g. }
- W4313280070 endingPage "161028" @default.
- W4313280070 startingPage "161028" @default.
- W4313280070 abstract "Endometriosis is a disease affecting 10-15 % of women worldwide, consisting in the ectopic growth of endometrial cells outside the uterine cavity. Whist the pathogenetic mechanisms of endometriosis remain elusive and contemplating even environmental causes, iron deposits are common in endometrial lesions, indicating an altered iron metabolism at this level. This study was undertaken to reveal a possible relationship between iron dysmetabolism and accumulation of environmental metals.By combining histological and histochemical analysis (H&E and Perl's staining) with μ- and nano- synchrotron-based (SR-based) X-ray Fluorescence (XRF) microscopy, we investigated the distribution of iron and other elements in the ovarian endometriomas of 12 endometriosis patients and in 7 healthy endometrium samples.XRF microscopy expanded the findings obtained by Perl's staining, revealing with an exceptional sensitivity intracellular features of iron accumulation in the epithelial endometrium, stroma and macrophages of the endometriotic lesions. XRF evidenced that iron was specifically accumulated in multiple micro aggregates, reaching concentrations up to 10-20 % p/p. Moreover, by XRF analysis we revealed for the first time the retention of a number of exogenous and potentially toxic metals such as Pb, Br, Ti, Al Cr, Si and Rb partially or totally co-localizing with iron.μXRF reveals accumulation and colocalization of iron and environmental metals in human ovarian endometriosis, suggesting a role in the pathogenesis of endometriosis." @default.
- W4313280070 created "2023-01-06" @default.
- W4313280070 creator A5006969279 @default.
- W4313280070 creator A5015204476 @default.
- W4313280070 creator A5026204894 @default.
- W4313280070 creator A5031526203 @default.
- W4313280070 creator A5034422853 @default.
- W4313280070 creator A5040066504 @default.
- W4313280070 creator A5042218633 @default.
- W4313280070 creator A5045025636 @default.
- W4313280070 creator A5047180009 @default.
- W4313280070 creator A5056963397 @default.
- W4313280070 creator A5057167754 @default.
- W4313280070 creator A5080412392 @default.
- W4313280070 creator A5083863497 @default.
- W4313280070 date "2023-03-01" @default.
- W4313280070 modified "2023-10-17" @default.
- W4313280070 title "Detention and mapping of iron and toxic environmental elements in human ovarian endometriosis: A suggested combined role" @default.
- W4313280070 cites W1238750936 @default.
- W4313280070 cites W1559399430 @default.
- W4313280070 cites W1727395646 @default.
- W4313280070 cites W1981530838 @default.
- W4313280070 cites W1984482196 @default.
- W4313280070 cites W1994213943 @default.
- W4313280070 cites W1996123579 @default.
- W4313280070 cites W2004914509 @default.
- W4313280070 cites W2009651345 @default.
- W4313280070 cites W2019585530 @default.
- W4313280070 cites W2028971906 @default.
- W4313280070 cites W2053849251 @default.
- W4313280070 cites W2057596304 @default.
- W4313280070 cites W2064286496 @default.
- W4313280070 cites W2075038784 @default.
- W4313280070 cites W2081977076 @default.
- W4313280070 cites W2092348451 @default.
- W4313280070 cites W2093105965 @default.
- W4313280070 cites W2108693844 @default.
- W4313280070 cites W2119501943 @default.
- W4313280070 cites W2121194203 @default.
- W4313280070 cites W2131489846 @default.
- W4313280070 cites W2161181985 @default.
- W4313280070 cites W2194235565 @default.
- W4313280070 cites W2269270215 @default.
- W4313280070 cites W2283357544 @default.
- W4313280070 cites W2341654050 @default.
- W4313280070 cites W2345124960 @default.
- W4313280070 cites W2415476931 @default.
- W4313280070 cites W2472961939 @default.
- W4313280070 cites W2530599254 @default.
- W4313280070 cites W2572323787 @default.
- W4313280070 cites W2605912824 @default.
- W4313280070 cites W2754055756 @default.
- W4313280070 cites W2794339668 @default.
- W4313280070 cites W2900983954 @default.
- W4313280070 cites W2953037856 @default.
- W4313280070 cites W2971693998 @default.
- W4313280070 cites W2995081392 @default.
- W4313280070 cites W3008713685 @default.
- W4313280070 cites W3086243400 @default.
- W4313280070 cites W3205039963 @default.
- W4313280070 cites W3208325566 @default.
- W4313280070 cites W4231488642 @default.
- W4313280070 cites W4234160457 @default.
- W4313280070 cites W777441029 @default.
- W4313280070 cites W796777251 @default.
- W4313280070 doi "https://doi.org/10.1016/j.scitotenv.2022.161028" @default.
- W4313280070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36549535" @default.
- W4313280070 hasPublicationYear "2023" @default.
- W4313280070 type Work @default.
- W4313280070 citedByCount "2" @default.
- W4313280070 countsByYear W43132800702023 @default.
- W4313280070 crossrefType "journal-article" @default.
- W4313280070 hasAuthorship W4313280070A5006969279 @default.
- W4313280070 hasAuthorship W4313280070A5015204476 @default.
- W4313280070 hasAuthorship W4313280070A5026204894 @default.
- W4313280070 hasAuthorship W4313280070A5031526203 @default.
- W4313280070 hasAuthorship W4313280070A5034422853 @default.
- W4313280070 hasAuthorship W4313280070A5040066504 @default.
- W4313280070 hasAuthorship W4313280070A5042218633 @default.
- W4313280070 hasAuthorship W4313280070A5045025636 @default.
- W4313280070 hasAuthorship W4313280070A5047180009 @default.
- W4313280070 hasAuthorship W4313280070A5056963397 @default.
- W4313280070 hasAuthorship W4313280070A5057167754 @default.
- W4313280070 hasAuthorship W4313280070A5080412392 @default.
- W4313280070 hasAuthorship W4313280070A5083863497 @default.
- W4313280070 hasBestOaLocation W43132800701 @default.
- W4313280070 hasConcept C134018914 @default.
- W4313280070 hasConcept C142724271 @default.
- W4313280070 hasConcept C185592680 @default.
- W4313280070 hasConcept C204232928 @default.
- W4313280070 hasConcept C2779522080 @default.
- W4313280070 hasConcept C2779742232 @default.
- W4313280070 hasConcept C2780820263 @default.
- W4313280070 hasConcept C2780942790 @default.
- W4313280070 hasConcept C2909208804 @default.
- W4313280070 hasConcept C40209533 @default.
- W4313280070 hasConcept C505870484 @default.
- W4313280070 hasConcept C52124034 @default.