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- W4313288364 abstract "Monosialoganglioside GM1-bound amyloid β-peptides have been found in patients’ brains exhibiting early pathological changes of Alzheimer’ s disease. Herein, we report the ability of non-micellar GM1 to modulate Aβ 40 aggregation resulting in the formation of stable, short, rod-like, and cytotoxic Aβ 40 protofibrils with the ability to potentiate both Aβ 40 and Aβ 42 aggregation." @default.
- W4313288364 created "2023-01-06" @default.
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- W4313288364 date "2022-12-29" @default.
- W4313288364 modified "2023-09-25" @default.
- W4313288364 title "Ganglioside GM1 produces stable, short, and cytotoxic Aβ<sub>40</sub>protofibrils" @default.
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- W4313288364 doi "https://doi.org/10.1101/2022.12.28.522135" @default.
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