Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313290078> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W4313290078 endingPage "154" @default.
- W4313290078 startingPage "150" @default.
- W4313290078 abstract "Introduction: The association between bisphosphonates and osteonecrosis of the jaws has been widely reported in the literature. Despite the higher incidence and the poor prognosis in cancer patients, there is still little understanding of risk factors for infectious complications in these patients. Objective: Evaluate the factors associated with infectious events related to osteonecrosis induced by zoledronic acid (ZA) in oncological patients. Methods: It was a retrospective, longitudinal and observational study that included 21 patients and collected the following variables: age; oncological disease; classification of necrosis; affected bone; triggering factor; frequency of ZA use; the number of ZA doses at the time of necrosis; smoking; cancer activity at the time of necrosis; use of corticosteroids; previous or current treatment with chemotherapy, immunosuppressive and antiangiogenics drugs. The outcome of interest was the number of new infection episodes. Results: 33% of patients showed only one infectious event after MRONJ diagnosis, 28.6% of the cases had two, 19% - four, 9.5% - three, one patient had six and another seven infection episodes. Among all the studied variables only the classification of osteonecrosis, Class.2 + 3: 2.06 (±2.08) vs. Class. 1: 0.00 (±0.54)-p: 0.05 and the frequency of ZA use, Monthly: 2.09 (±1.64) vs. Quarterly: 0.25 (±0.46)-p: 0.002 showed highest incidence of infectious events. In the binary logistic regression, monthly use of bisphosphonate (OR:15; 1.34-16.64) and necrosis in the mandible (OR:10.8; 1.0-11.7) were associated with infection. Conclusion: MRONJ in cancer patients can be associated with recurrent infections and mandibular involvement, and monthly ZA use is potential risk factor for poor prognosis." @default.
- W4313290078 created "2023-01-06" @default.
- W4313290078 creator A5039165220 @default.
- W4313290078 creator A5064101963 @default.
- W4313290078 creator A5076224727 @default.
- W4313290078 creator A5077227987 @default.
- W4313290078 creator A5087178547 @default.
- W4313290078 creator A5089086026 @default.
- W4313290078 date "2022-12-23" @default.
- W4313290078 modified "2023-10-18" @default.
- W4313290078 title "Infections in cancer patients with medication-related osteonecrosis of the jaws" @default.
- W4313290078 cites W1536865010 @default.
- W4313290078 cites W1957467225 @default.
- W4313290078 cites W2058273933 @default.
- W4313290078 cites W2058889454 @default.
- W4313290078 cites W2076370157 @default.
- W4313290078 cites W2088311496 @default.
- W4313290078 cites W2119269455 @default.
- W4313290078 cites W2122972229 @default.
- W4313290078 cites W2128225972 @default.
- W4313290078 cites W2143254775 @default.
- W4313290078 cites W2150904792 @default.
- W4313290078 cites W2160102488 @default.
- W4313290078 cites W2169512870 @default.
- W4313290078 cites W2173450587 @default.
- W4313290078 cites W2292474808 @default.
- W4313290078 cites W2343274873 @default.
- W4313290078 cites W2510178775 @default.
- W4313290078 cites W2568284838 @default.
- W4313290078 cites W2579319657 @default.
- W4313290078 cites W2609800424 @default.
- W4313290078 cites W2623508374 @default.
- W4313290078 cites W2727242048 @default.
- W4313290078 cites W2740475325 @default.
- W4313290078 cites W2800759082 @default.
- W4313290078 cites W2809432603 @default.
- W4313290078 cites W2884689271 @default.
- W4313290078 cites W2885913123 @default.
- W4313290078 cites W2889090899 @default.
- W4313290078 cites W2899988391 @default.
- W4313290078 doi "https://doi.org/10.15406/jcpcr.2022.13.00505" @default.
- W4313290078 hasPublicationYear "2022" @default.
- W4313290078 type Work @default.
- W4313290078 citedByCount "0" @default.
- W4313290078 crossrefType "journal-article" @default.
- W4313290078 hasAuthorship W4313290078A5039165220 @default.
- W4313290078 hasAuthorship W4313290078A5064101963 @default.
- W4313290078 hasAuthorship W4313290078A5076224727 @default.
- W4313290078 hasAuthorship W4313290078A5077227987 @default.
- W4313290078 hasAuthorship W4313290078A5087178547 @default.
- W4313290078 hasAuthorship W4313290078A5089086026 @default.
- W4313290078 hasBestOaLocation W43132900781 @default.
- W4313290078 hasConcept C121608353 @default.
- W4313290078 hasConcept C126322002 @default.
- W4313290078 hasConcept C143998085 @default.
- W4313290078 hasConcept C177713679 @default.
- W4313290078 hasConcept C199343813 @default.
- W4313290078 hasConcept C2776598537 @default.
- W4313290078 hasConcept C2780140570 @default.
- W4313290078 hasConcept C2780435969 @default.
- W4313290078 hasConcept C2994114330 @default.
- W4313290078 hasConcept C43138044 @default.
- W4313290078 hasConcept C71924100 @default.
- W4313290078 hasConceptScore W4313290078C121608353 @default.
- W4313290078 hasConceptScore W4313290078C126322002 @default.
- W4313290078 hasConceptScore W4313290078C143998085 @default.
- W4313290078 hasConceptScore W4313290078C177713679 @default.
- W4313290078 hasConceptScore W4313290078C199343813 @default.
- W4313290078 hasConceptScore W4313290078C2776598537 @default.
- W4313290078 hasConceptScore W4313290078C2780140570 @default.
- W4313290078 hasConceptScore W4313290078C2780435969 @default.
- W4313290078 hasConceptScore W4313290078C2994114330 @default.
- W4313290078 hasConceptScore W4313290078C43138044 @default.
- W4313290078 hasConceptScore W4313290078C71924100 @default.
- W4313290078 hasIssue "6" @default.
- W4313290078 hasLocation W43132900781 @default.
- W4313290078 hasOpenAccess W4313290078 @default.
- W4313290078 hasPrimaryLocation W43132900781 @default.
- W4313290078 hasRelatedWork W1955136089 @default.
- W4313290078 hasRelatedWork W2132239150 @default.
- W4313290078 hasRelatedWork W2175526374 @default.
- W4313290078 hasRelatedWork W2317459963 @default.
- W4313290078 hasRelatedWork W2343109697 @default.
- W4313290078 hasRelatedWork W2399058385 @default.
- W4313290078 hasRelatedWork W2886552132 @default.
- W4313290078 hasRelatedWork W2890274714 @default.
- W4313290078 hasRelatedWork W4251735599 @default.
- W4313290078 hasRelatedWork W4315797179 @default.
- W4313290078 hasVolume "13" @default.
- W4313290078 isParatext "false" @default.
- W4313290078 isRetracted "false" @default.
- W4313290078 workType "article" @default.