Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313303048> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4313303048 endingPage "13" @default.
- W4313303048 startingPage "3" @default.
- W4313303048 abstract "The use of liposomal nanoparticles as a drug delivery system today is a promising area of modern nanopharmacology, in particular in the development of antitumor drugs. Liposomal forms of antitumor active pharmaceutical ingredients are characterized by reduced toxicity, stability, and increased antitumor activity of nanoparticle-encapsulated antitumor agent, prolonged action of the drug. Commercially available liposomal anticancer drugs are passively targeted drugs that accumulate in cells by passive diffusion in tumor cells due to the EPR effect of the vascular system. This review presents data from the study of antitumor activity of liposomal drugs conducted by Ukrainian scientists in recent decades. Today, the antitumor activity of liposomal forms of therapeutic agents of various natures has been proven, among them are anthracycline antibiotics, platinum drugs, semisynthetic alkaloid derivatives, natural polyphenolic antioxidants, etc. Thus, the encapsulation of doxorubicin hydrochloride in liposomes has reduced its cardiotoxicity and other side effects, provided an opportunity to treat doxorubicin-resistant tumors. Liposomal forms of complex platinum compounds, in particular cisplatin, have been shown to be more effective than free forms of cytostatics in the treatment of cisplatin-resistant ovarian cancer. The use of polyphenolic antioxidants, quercetin and curcumin, in complex therapy can not only enhance the antitumor effect, but also have a protective effect on healthy tissues and organs." @default.
- W4313303048 created "2023-01-06" @default.
- W4313303048 creator A5024843089 @default.
- W4313303048 creator A5036120219 @default.
- W4313303048 creator A5081877624 @default.
- W4313303048 date "2022-12-30" @default.
- W4313303048 modified "2023-09-30" @default.
- W4313303048 title "NANOMEDICINE IN ANTICANCER THERAPY" @default.
- W4313303048 doi "https://doi.org/10.20998/2079-0821.2022.01" @default.
- W4313303048 hasPublicationYear "2022" @default.
- W4313303048 type Work @default.
- W4313303048 citedByCount "0" @default.
- W4313303048 crossrefType "journal-article" @default.
- W4313303048 hasAuthorship W4313303048A5024843089 @default.
- W4313303048 hasAuthorship W4313303048A5036120219 @default.
- W4313303048 hasAuthorship W4313303048A5081877624 @default.
- W4313303048 hasBestOaLocation W43133030481 @default.
- W4313303048 hasConcept C126322002 @default.
- W4313303048 hasConcept C15083742 @default.
- W4313303048 hasConcept C155672457 @default.
- W4313303048 hasConcept C171250308 @default.
- W4313303048 hasConcept C178790620 @default.
- W4313303048 hasConcept C185154212 @default.
- W4313303048 hasConcept C185592680 @default.
- W4313303048 hasConcept C192562407 @default.
- W4313303048 hasConcept C2776694085 @default.
- W4313303048 hasConcept C2778233292 @default.
- W4313303048 hasConcept C2778239845 @default.
- W4313303048 hasConcept C2778250585 @default.
- W4313303048 hasConcept C2779820397 @default.
- W4313303048 hasConcept C2780035454 @default.
- W4313303048 hasConcept C2781021840 @default.
- W4313303048 hasConcept C2781303535 @default.
- W4313303048 hasConcept C2909829705 @default.
- W4313303048 hasConcept C55493867 @default.
- W4313303048 hasConcept C71924100 @default.
- W4313303048 hasConcept C98274493 @default.
- W4313303048 hasConceptScore W4313303048C126322002 @default.
- W4313303048 hasConceptScore W4313303048C15083742 @default.
- W4313303048 hasConceptScore W4313303048C155672457 @default.
- W4313303048 hasConceptScore W4313303048C171250308 @default.
- W4313303048 hasConceptScore W4313303048C178790620 @default.
- W4313303048 hasConceptScore W4313303048C185154212 @default.
- W4313303048 hasConceptScore W4313303048C185592680 @default.
- W4313303048 hasConceptScore W4313303048C192562407 @default.
- W4313303048 hasConceptScore W4313303048C2776694085 @default.
- W4313303048 hasConceptScore W4313303048C2778233292 @default.
- W4313303048 hasConceptScore W4313303048C2778239845 @default.
- W4313303048 hasConceptScore W4313303048C2778250585 @default.
- W4313303048 hasConceptScore W4313303048C2779820397 @default.
- W4313303048 hasConceptScore W4313303048C2780035454 @default.
- W4313303048 hasConceptScore W4313303048C2781021840 @default.
- W4313303048 hasConceptScore W4313303048C2781303535 @default.
- W4313303048 hasConceptScore W4313303048C2909829705 @default.
- W4313303048 hasConceptScore W4313303048C55493867 @default.
- W4313303048 hasConceptScore W4313303048C71924100 @default.
- W4313303048 hasConceptScore W4313303048C98274493 @default.
- W4313303048 hasIssue "7" @default.
- W4313303048 hasLocation W43133030481 @default.
- W4313303048 hasOpenAccess W4313303048 @default.
- W4313303048 hasPrimaryLocation W43133030481 @default.
- W4313303048 hasRelatedWork W1492185019 @default.
- W4313303048 hasRelatedWork W18137048 @default.
- W4313303048 hasRelatedWork W1988382716 @default.
- W4313303048 hasRelatedWork W2035096408 @default.
- W4313303048 hasRelatedWork W2093442802 @default.
- W4313303048 hasRelatedWork W2305100815 @default.
- W4313303048 hasRelatedWork W4210691215 @default.
- W4313303048 hasRelatedWork W4213331136 @default.
- W4313303048 hasRelatedWork W4308740090 @default.
- W4313303048 hasRelatedWork W4313303048 @default.
- W4313303048 hasVolume "1" @default.
- W4313303048 isParatext "false" @default.
- W4313303048 isRetracted "false" @default.
- W4313303048 workType "article" @default.