FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313303975> ?p ?o ?g. }

• W4313303975 abstract "Abstract Background Polycystic ovary syndrome (PCOS) is an endocrine-metabolic disorder that affects women at their child bearing age. The exact etiology is uncertain, however the involvement of multiple genes and environmental interactions has been proposed for the advancement of PCOS. The aim of present study was to evaluate the association of LHCGR variants (rs2293275 and rs12470652) with PCOS in Punjab. Methods The present case–control study comprised a total of 743 women (421 PCOS cases and 322 healthy controls). Genotyping was performed using polymerase chain reaction-restriction fragment length polymorphism technique (PCR–RFLP). Biochemical analysis was carried out to measure the levels of cholesterol, High-density lipoprotein (HDL), Low-density lipoprotein (LDL), Very low-density lipoprotein (VLDL), triglycerides, testosterone, luteinizing hormone (LH) and follicle-stimulating hormone (FSH). All the statistical analysis was done using SPSS (version21, IBM SPSS, NY, USA). Results The mutant genotype (AA) and mutant allele (A) of rs2293275 conferred 1.7 and 1.3 fold risk, respectively and mutant allele (C) of rs12470652 conferred 2.3 fold risks towards PCOS progression. Levels of cholesterol and triglycerides were elevated and HDL levels were lower in PCOS cases as compared to controls. Total testosterone and luteinizing hormone levels were also found to be higher in PCOS cases. Conclusion Our study postulated that LHCGR variants are playing a cardinal role in the progression of PCOS and can be used to assess the risk of PCOS in women of reproductive age." @default.
• W4313303975 created "2023-01-06" @default.
• W4313303975 creator A5035324198 @default.
• W4313303975 creator A5037238575 @default.
• W4313303975 creator A5070649426 @default.
• W4313303975 creator A5071482164 @default.
• W4313303975 creator A5075923555 @default.
• W4313303975 date "2022-12-30" @default.
• W4313303975 modified "2023-10-18" @default.
• W4313303975 title "Association analysis of LHCGR variants and polycystic ovary syndrome in Punjab: a case–control approach" @default.
• W4313303975 cites W1560681487 @default.
• W4313303975 cites W1567510481 @default.
• W4313303975 cites W1973928540 @default.
• W4313303975 cites W1986422582 @default.
• W4313303975 cites W1990974280 @default.
• W4313303975 cites W2017602185 @default.
• W4313303975 cites W2024895018 @default.
• W4313303975 cites W2028547572 @default.
• W4313303975 cites W2031111555 @default.
• W4313303975 cites W2043300506 @default.
• W4313303975 cites W2051209291 @default.
• W4313303975 cites W2056399290 @default.
• W4313303975 cites W2058667120 @default.
• W4313303975 cites W2062863385 @default.
• W4313303975 cites W2066964651 @default.
• W4313303975 cites W2076225622 @default.
• W4313303975 cites W2077503759 @default.
• W4313303975 cites W2099716386 @default.
• W4313303975 cites W2102668036 @default.
• W4313303975 cites W2113329249 @default.
• W4313303975 cites W2116404316 @default.
• W4313303975 cites W2125872854 @default.
• W4313303975 cites W2126631212 @default.
• W4313303975 cites W2138614192 @default.
• W4313303975 cites W2140126911 @default.
• W4313303975 cites W2140354199 @default.
• W4313303975 cites W2140659875 @default.
• W4313303975 cites W2163745787 @default.
• W4313303975 cites W2183699512 @default.
• W4313303975 cites W2186218348 @default.
• W4313303975 cites W2275092747 @default.
• W4313303975 cites W2280501212 @default.
• W4313303975 cites W2310760875 @default.
• W4313303975 cites W2334634018 @default.
• W4313303975 cites W2594746751 @default.
• W4313303975 cites W2741878389 @default.
• W4313303975 cites W2754883246 @default.
• W4313303975 cites W2890778093 @default.
• W4313303975 cites W2900507018 @default.
• W4313303975 cites W2907159400 @default.
• W4313303975 cites W2919517036 @default.
• W4313303975 cites W3023457302 @default.
• W4313303975 cites W3087087963 @default.
• W4313303975 cites W3118630608 @default.
• W4313303975 cites W3204167133 @default.
• W4313303975 cites W4221056585 @default.
• W4313303975 cites W4283757715 @default.
• W4313303975 doi "https://doi.org/10.1186/s12902-022-01251-9" @default.
• W4313303975 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36585675" @default.
• W4313303975 hasPublicationYear "2022" @default.
• W4313303975 type Work @default.
• W4313303975 citedByCount "1" @default.
• W4313303975 countsByYear W43133039752023 @default.
• W4313303975 crossrefType "journal-article" @default.
• W4313303975 hasAuthorship W4313303975A5035324198 @default.
• W4313303975 hasAuthorship W4313303975A5037238575 @default.
• W4313303975 hasAuthorship W4313303975A5070649426 @default.
• W4313303975 hasAuthorship W4313303975A5071482164 @default.
• W4313303975 hasAuthorship W4313303975A5075923555 @default.
• W4313303975 hasBestOaLocation W43133039751 @default.
• W4313303975 hasConcept C104317684 @default.
• W4313303975 hasConcept C126322002 @default.
• W4313303975 hasConcept C134018914 @default.
• W4313303975 hasConcept C135763542 @default.
• W4313303975 hasConcept C2777391703 @default.
• W4313303975 hasConcept C2778163477 @default.
• W4313303975 hasConcept C2778575703 @default.
• W4313303975 hasConcept C2779279991 @default.
• W4313303975 hasConcept C2780541478 @default.
• W4313303975 hasConcept C3018442814 @default.
• W4313303975 hasConcept C42407357 @default.
• W4313303975 hasConcept C54355233 @default.
• W4313303975 hasConcept C555293320 @default.
• W4313303975 hasConcept C71315377 @default.
• W4313303975 hasConcept C71924100 @default.
• W4313303975 hasConcept C86803240 @default.
• W4313303975 hasConceptScore W4313303975C104317684 @default.
• W4313303975 hasConceptScore W4313303975C126322002 @default.
• W4313303975 hasConceptScore W4313303975C134018914 @default.
• W4313303975 hasConceptScore W4313303975C135763542 @default.
• W4313303975 hasConceptScore W4313303975C2777391703 @default.
• W4313303975 hasConceptScore W4313303975C2778163477 @default.
• W4313303975 hasConceptScore W4313303975C2778575703 @default.
• W4313303975 hasConceptScore W4313303975C2779279991 @default.
• W4313303975 hasConceptScore W4313303975C2780541478 @default.
• W4313303975 hasConceptScore W4313303975C3018442814 @default.
• W4313303975 hasConceptScore W4313303975C42407357 @default.
• W4313303975 hasConceptScore W4313303975C54355233 @default.
• W4313303975 hasConceptScore W4313303975C555293320 @default.
• W4313303975 hasConceptScore W4313303975C71315377 @default.

• next