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- W4313306901 abstract "Abstract It is not yet clear whether or not skin-sensitizing antibody requires the complement system when it fixes to the cutaneous site in the Prausnitz-Küstner (PK) reaction. Attempts to analyze in vivo the role of complement in various immunologic phenomena have been carried out employing specific inhibitors of complement components (1). The effect of C′3 inactivator and Cu-chlorophyllin (CuC) on the PK reaction was examined. The results are described in this report. C′3 inactivator is the substance which inactivates the C′3 site of EAC′1423 both in immune adherence and in immune hemolysis (2). It was purified from human serum using column chromatography on diethylaminoethyl (DEAE)-cellulose and carboxymethyl (CM)-cellulose, followed by Sepadex G 200 and Sephadex G 200 super-fine gel filtration (3). The titer of C′3 inactivator was measured by a method previously described (4). Sodium copper chlorophyllin was shown to be a potent inhibitor in both immune hemolysis and passive cutaneous anaphylaxis (PCA) (1, 5)." @default.
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- W4313306901 date "1968-11-01" @default.
- W4313306901 modified "2023-10-14" @default.
- W4313306901 title "Communications" @default.
- W4313306901 doi "https://doi.org/10.4049/jimmunol.101.5.1095" @default.
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