Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313306945> ?p ?o ?g. }
Showing items 1 to 53 of
53
with 100 items per page.
- W4313306945 endingPage "489" @default.
- W4313306945 startingPage "476" @default.
- W4313306945 abstract "Abstract Two mechanisms have been described by which antigen-antibody complexes in the presence of complement induce release of vasoactive amines from rabbit platelets. The reaction of soluble antigen, antibody in excess, normal rabbit plasma and platelets caused adherence of the platelets to the immune complexes (which required the action of C3) and lysis of the platelets (which required the action of C6). The lysis was observed microscopically and was accompanied by release of vasoactive amines, nucleotides and cytoplasmic and lysosomal enzymes. The release did not require active participation of the platelet and was postulated to result from cell lysis by complement components activated by the immune complexes in or on the platelet membrane. A nonlytic, complement-dependent release of vasoactive amines resulted from immune adherence of platelets to erythrocytes or zymosan that had fixed complement components through C3. Vasoactive amines and nucleotides were released by the reaction, but not intracellular enzymes or potassium (measured with rubidium 86). Platelet energy and activated platelet esterases were required for the release, which appeared to result from the C3-induced adherence of the platelets to the particulate antigens." @default.
- W4313306945 created "2023-01-06" @default.
- W4313306945 creator A5030906578 @default.
- W4313306945 date "1970-08-01" @default.
- W4313306945 modified "2023-10-18" @default.
- W4313306945 title "Mechanisms of Release of Constituents from Rabbit Platelets by Antigen-Antibody Complexes and Complement" @default.
- W4313306945 doi "https://doi.org/10.4049/jimmunol.105.2.476" @default.
- W4313306945 hasPublicationYear "1970" @default.
- W4313306945 type Work @default.
- W4313306945 citedByCount "30" @default.
- W4313306945 crossrefType "journal-article" @default.
- W4313306945 hasAuthorship W4313306945A5030906578 @default.
- W4313306945 hasBestOaLocation W43133069451 @default.
- W4313306945 hasConcept C147483822 @default.
- W4313306945 hasConcept C153911025 @default.
- W4313306945 hasConcept C159654299 @default.
- W4313306945 hasConcept C185592680 @default.
- W4313306945 hasConcept C203014093 @default.
- W4313306945 hasConcept C55493867 @default.
- W4313306945 hasConcept C57409179 @default.
- W4313306945 hasConcept C86803240 @default.
- W4313306945 hasConcept C8891405 @default.
- W4313306945 hasConcept C89560881 @default.
- W4313306945 hasConceptScore W4313306945C147483822 @default.
- W4313306945 hasConceptScore W4313306945C153911025 @default.
- W4313306945 hasConceptScore W4313306945C159654299 @default.
- W4313306945 hasConceptScore W4313306945C185592680 @default.
- W4313306945 hasConceptScore W4313306945C203014093 @default.
- W4313306945 hasConceptScore W4313306945C55493867 @default.
- W4313306945 hasConceptScore W4313306945C57409179 @default.
- W4313306945 hasConceptScore W4313306945C86803240 @default.
- W4313306945 hasConceptScore W4313306945C8891405 @default.
- W4313306945 hasConceptScore W4313306945C89560881 @default.
- W4313306945 hasIssue "2" @default.
- W4313306945 hasLocation W43133069451 @default.
- W4313306945 hasOpenAccess W4313306945 @default.
- W4313306945 hasPrimaryLocation W43133069451 @default.
- W4313306945 hasRelatedWork W1532337558 @default.
- W4313306945 hasRelatedWork W2049373341 @default.
- W4313306945 hasRelatedWork W2323665869 @default.
- W4313306945 hasRelatedWork W2363187064 @default.
- W4313306945 hasRelatedWork W2366789888 @default.
- W4313306945 hasRelatedWork W2368415432 @default.
- W4313306945 hasRelatedWork W2599617414 @default.
- W4313306945 hasRelatedWork W3033187003 @default.
- W4313306945 hasRelatedWork W3157018711 @default.
- W4313306945 hasRelatedWork W4220899353 @default.
- W4313306945 hasVolume "105" @default.
- W4313306945 isParatext "false" @default.
- W4313306945 isRetracted "false" @default.
- W4313306945 workType "article" @default.