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- W4313307098 abstract "Summary After oxidative sulfitolysis of normal rabbit IgG, two fractions (LI and LII) of light chains were separated by gel filtration on Sephadex G 100 in acid-urea. More than half of the light chains in the LI fraction (b-n) lacked antigenic determinants associated with the b locus (b+) and shared antigenic determinants with a distinct type of light chain (b-s) previously isolated from the sera of rabbits suppressed for genetic expression of b locus allotypes. The LII fraction, representing about 80% of the total light chain population from normal b5 rabbits, was found to be largely if not entirely composed of b+ light chains. Both b-n and b-s light chains were found to be antigenically distinct from b+ light chains. This supports the hypothesis that rabbit b- light chains obtained from normal or suppressed rabbits correspond to λ type chains." @default.
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- W4313307098 date "1969-03-01" @default.
- W4313307098 modified "2023-10-17" @default.
- W4313307098 title "Rabbit Light Chains Lacking b-Allotypic Specificities" @default.
- W4313307098 doi "https://doi.org/10.4049/jimmunol.102.3.638" @default.
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