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- W4313307470 abstract "Abstract A 5- to 7-day incubation of heavily irradiated (2000 R) human leukocytes yielded a macrophage-rich population which was capable of markedly increasing blastogenic reactivity to PPD (purified protein derivative) of lymphocytes from sensitive donors as measured by incorporation of tritiated thymidine. These radioresistant cells were also demonstrated in some donors to be capable of initiating the blastogenic response after being only briefly exposed to antigen. This activity was demonstrable only when these cells were intact, viable, in direct contact with the lymphocytes and pulsed with antigen sometime within the preceding 72 hr. This ability to initiate blastogenesis in lymphocytes was inhibited if macrophage exposure to antigen occurred at low temperature or in the presence of actinomycin D or cyanide." @default.
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- W4313307470 date "1970-09-01" @default.
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- W4313307470 title "Interaction of Lymphocytes and a Radioresistant Cell in PPD-Stimulated Human Leukocyte Cultures" @default.
- W4313307470 doi "https://doi.org/10.4049/jimmunol.105.3.661" @default.
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