Matches in SemOpenAlex for { <https://semopenalex.org/work/W4313307864> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W4313307864 endingPage "442" @default.
- W4313307864 startingPage "429" @default.
- W4313307864 abstract "Summary The results of this study conducted with one culture of treponema pallidum may be summarized as follows: Fresh active normal serum exerts no treponemicidal action on culture pallida in vitro in the proportion of one or two parts of serum to one part of diluted fluid culture.The sera of persons in the tertiary and latent stages of syphilis exert no appreciable treponemicidal action on culture pallida in vitro under similar conditions.The sera of syphilitic persons yielding typical luetin reactions did not exert any treponemicidal activity in vitro.There is no direct relation between the occurrence of cutaneous hypersensitiveness to luetin and the presence of agglutinin for culture pallida in the blood serum.There is no direct relation between the occurrence of cutaneous hypersensitiveness to luetin and the presence of a complement-fixing antibody with an antigen of luetin in the blood serum; both the anaphylactic and complement-fixing antibodies were present or absent together in 52 per cent of cases, while the former was present and the latter absent in 40 per cent. The anaphylactic and complement-fixation reactions indicate an infection with treponema pallidum, but as based upon experiments in vitro neither can be regarded as indicating the co-existence of a treponemolysin or as an index of immunity to syphilis.The sera of a larger percentage of syphilitics contain agglutinin for treponema pallidum than complement-fixing antibody when luetin is used as antigen. It is probable that this difference is due in large part to the poor antigenic sensitiveness of luetin as antigen; when ordinary lipoidal extracts were used as antigens both complement fixation and agglutination occurred together with the majority of sera.As based mainly upon the results of these treponemicidal and other tests in vitro, the anaphylactic luetin test cannot be regarded as an index of resistance to treponema pallidum; these experiments and the failure of others (Neisser and Bruck; Nakano and Noguchi) to produce active immunity in animals to syphilis indicate that a lytic type of immunity is absent in syphilis or, at least, that it plays but a minor rôle in this infection." @default.
- W4313307864 created "2023-01-06" @default.
- W4313307864 creator A5018780865 @default.
- W4313307864 creator A5019363633 @default.
- W4313307864 date "1916-08-01" @default.
- W4313307864 modified "2023-10-16" @default.
- W4313307864 title "The Relation of the Luetin Skin Reaction to Immunity in Syphilis (Including the Treponemicidal Action of Human Serum in Syphilis)" @default.
- W4313307864 doi "https://doi.org/10.4049/jimmunol.1.4.429" @default.
- W4313307864 hasPublicationYear "1916" @default.
- W4313307864 type Work @default.
- W4313307864 citedByCount "0" @default.
- W4313307864 crossrefType "journal-article" @default.
- W4313307864 hasAuthorship W4313307864A5018780865 @default.
- W4313307864 hasAuthorship W4313307864A5019363633 @default.
- W4313307864 hasBestOaLocation W43133078641 @default.
- W4313307864 hasConcept C147483822 @default.
- W4313307864 hasConcept C152669594 @default.
- W4313307864 hasConcept C159047783 @default.
- W4313307864 hasConcept C159654299 @default.
- W4313307864 hasConcept C202751555 @default.
- W4313307864 hasConcept C203014093 @default.
- W4313307864 hasConcept C207545495 @default.
- W4313307864 hasConcept C2776983459 @default.
- W4313307864 hasConcept C2779341262 @default.
- W4313307864 hasConcept C2780187896 @default.
- W4313307864 hasConcept C2780758401 @default.
- W4313307864 hasConcept C3013748606 @default.
- W4313307864 hasConcept C45189115 @default.
- W4313307864 hasConcept C55493867 @default.
- W4313307864 hasConcept C86803240 @default.
- W4313307864 hasConcept C8891405 @default.
- W4313307864 hasConcept C89423630 @default.
- W4313307864 hasConceptScore W4313307864C147483822 @default.
- W4313307864 hasConceptScore W4313307864C152669594 @default.
- W4313307864 hasConceptScore W4313307864C159047783 @default.
- W4313307864 hasConceptScore W4313307864C159654299 @default.
- W4313307864 hasConceptScore W4313307864C202751555 @default.
- W4313307864 hasConceptScore W4313307864C203014093 @default.
- W4313307864 hasConceptScore W4313307864C207545495 @default.
- W4313307864 hasConceptScore W4313307864C2776983459 @default.
- W4313307864 hasConceptScore W4313307864C2779341262 @default.
- W4313307864 hasConceptScore W4313307864C2780187896 @default.
- W4313307864 hasConceptScore W4313307864C2780758401 @default.
- W4313307864 hasConceptScore W4313307864C3013748606 @default.
- W4313307864 hasConceptScore W4313307864C45189115 @default.
- W4313307864 hasConceptScore W4313307864C55493867 @default.
- W4313307864 hasConceptScore W4313307864C86803240 @default.
- W4313307864 hasConceptScore W4313307864C8891405 @default.
- W4313307864 hasConceptScore W4313307864C89423630 @default.
- W4313307864 hasIssue "4" @default.
- W4313307864 hasLocation W43133078641 @default.
- W4313307864 hasOpenAccess W4313307864 @default.
- W4313307864 hasPrimaryLocation W43133078641 @default.
- W4313307864 hasRelatedWork W1558055361 @default.
- W4313307864 hasRelatedWork W1966181773 @default.
- W4313307864 hasRelatedWork W2017048165 @default.
- W4313307864 hasRelatedWork W2065598430 @default.
- W4313307864 hasRelatedWork W2416888569 @default.
- W4313307864 hasRelatedWork W2427966752 @default.
- W4313307864 hasRelatedWork W3030059099 @default.
- W4313307864 hasRelatedWork W3031549672 @default.
- W4313307864 hasRelatedWork W4313307864 @default.
- W4313307864 hasRelatedWork W81735257 @default.
- W4313307864 hasVolume "1" @default.
- W4313307864 isParatext "false" @default.
- W4313307864 isRetracted "false" @default.
- W4313307864 workType "article" @default.